Table 1 The enriched KEGG pathways in the E1HKs and E2HKs as revealed by Fisher’s exact test
KEGG pathway | Background | E1HKs | P value* E1HKs | E2HKs | P value* E2HKs |
|---|---|---|---|---|---|
Biofilm formation | 206 | 115 | 2.47E-19 | – | – |
Two-component system | 462 | 171 | 5.38E-14 | – | – |
ABC transporters | 431 | 160 | 2.97E-13 | – | – |
Phosphotransferase system (PTS) | 91 | 53 | 4.26E-10 | – | – |
Transcription factors | 508 | 154 | 1.40E-07 | – | – |
Bacterial motility proteins | 129 | 55 | 9.77E-07 | – | – |
Lipopolysaccharide biosynthesis proteins | 110 | 48 | 2.57E-06 | – | – |
Cationic antimicrobial peptide (CAMP) resistance | 50 | 28 | 1.10E-05 | – | – |
beta-Lactam resistance | 73 | 27 | 3.37E-03 | – | – |
Biosynthesis of siderophore group nonribosomal peptides | 29 | 13 | 0.02 | – | – |
Bacterial secretion system | 73 | 24 | 0.02 | – | – |
Sulfur relay system | 23 | 10 | 0.03 | – | – |
Ubiquinone and other terpenoid-quinone biosynthesis | 44 | 16 | 0.03 | – | – |
Bacterial chemotaxis | 26 | 11 | 0.04 | – | – |
Valine, leucine, and isoleucine degradation | 52 | – | – | 29 | 8.79E-06 |
Phenylalanine metabolism | 58 | – | – | 29 | 4.30E-05 |
Benzoate degradation | 86 | – | – | 35 | 2.24E-04 |
Aminobenzoate degradation | 65 | – | – | 29 | 2.78E-04 |
Methane metabolism | 127 | – | – | 45 | 4.39E-04 |
Glyoxylate and dicarboxylate metabolism | 83 | – | – | 33 | 4.65E-04 |
Tryptophan metabolism | 48 | – | – | 22 | 8.71E-04 |
Nitrogen metabolism | 51 | – | – | 22 | 1.84E-03 |
Cell cycle Caulobacter | 31 | – | – | 16 | 1.87E-03 |
Synthesis and degradation of ketone bodies | 8 | – | – | 7 | 4.79E-03 |
Butanoate metabolism | 81 | – | – | 28 | 7.63E-03 |
Fluorobenzoate degradation | 12 | – | – | 8 | 8.00E-03 |
Propanoate metabolism | 92 | – | – | 30 | 0.01 |
Xylene degradation | 32 | – | – | 14 | 0.01 |
Tyrosine metabolism | 51 | – | – | 19 | 0.01 |
Fatty acid degradation | 39 | – | – | 16 | 0.01 |
Geraniol degradation | 14 | – | – | 8 | 0.02 |
Oxidative phosphorylation | 125 | – | – | 37 | 0.02 |
Glucosinolate biosynthesis | 6 | – | – | 5 | 0.02 |
Vitamin B6 metabolism | 21 | – | – | 10 | 0.02 |
Caprolactam degradation | 18 | – | – | 9 | 0.03 |
Styrene degradation | 20 | – | – | 9 | 0.04 |
Isoquinoline alkaloid biosynthesis | 11 | – | – | 6 | 0.04 |
Limonene and pinene degradation | 8 | – | – | 5 | 0.04 |
Chlorocyclohexane and chlorobenzene degradation | 29 | – | – | 11 | 0.05 |