Table 2 GATA3 gene expression in relation to clinicopathological variables and ER-phosphorylation in ER-positive tumors
GATA3 gene expression by tertiles (T) | |||||
|---|---|---|---|---|---|
T1 | T2 | T3 | |||
n (%) | n (%) | n (%) | p-valuea | ||
Tamoxifen | Untreated | 83 (35) | 75 (31) | 82 (34) | |
Treated | 88 (32) | 96 (35) | 88 (32) | 0.95 | |
Tumor size | ≤20 mm | 137 (33) | 139 (34) | 138 (33) | |
≥20 mm | 31 (34) | 30 (33) | 31 (34) | 0.98 | |
PgR | <10% | 56 (37) | 38 (25) | 57 (38) | |
≥10% | 104 (33) | 115 (36) | 98 (31) | 0.76 | |
HER2 | Negative | 146 (32) | 151 (34) | 153 (34) | |
Positive | 18 (69) | 4 (15) | 4 (15) | 0.00076 (−) | |
pERs167 nuclear | Negative | 132 (35) | 121 (32) | 121 (32) | |
Positive | 33 (29) | 40 (35) | 40 (35) | 0.30 | |
pERs305 nuclear | Negative | 117 (39) | 99 (33) | 83 (28) | |
Positive | 44 (25) | 59 (33) | 76 (42) | 0.00014 | |