Fig. 1: Proteomic analysis of dECM.

A Venn diagram of proteins in dECMs of BCs (proteomic cohort) by ECM type and BC grade. Total numbers of proteins in each subgroup are also shown. B Heatmap of GO enrichment analysis by DAVID and Panther for differentially expressed proteins in E3G3 versus E3G0, E3G3 versus E0G3, and E0G3 versus E0G0. Only significant (p < 0.05) pathways are shown. Fold-enrichment is color-coded. C Principal component analysis for the total proteome of dECMs.