Fig. 5: Mutational events following T-DXd treatment. | npj Breast Cancer

Fig. 5: Mutational events following T-DXd treatment.

From: Mechanisms of resistance to trastuzumab deruxtecan in breast cancer elucidated by multi-omic molecular profiling

Fig. 5: Mutational events following T-DXd treatment.The alternative text for this image may have been generated using AI.

a Comparison of pre- and post-treatment molecular profiles. All mutations shown have p < 0.05 (unadjusted p value). *: q < 0.05; **: q < 0.005; ***: q < 0.0005. b Lollipop graphs showing gain-of-function mutations of NFE2L2 and c loss-of-function mutations in KEAP1.

Back to article page