Table 1 Patient clinicopathologic characteristics in the NCR and TEAM cohorts

From: Validation of minimal risk of recurrence classification by the Breast Cancer Index in early stage breast cancer

Characteristics

n (%)

NCR Cohort (n = 1264)

TEAM Cohort (n = 978)

Age at surgery, years

 Mean ± SD

78 ± 5

67 ± 8

 <50

0

4 (0.4)

 50–59

0

201 (20.6)

 60–69

0

419 (42.8)

 70–74

504 (39.9)

175 (17.9)

 75–79

273 (21.6)

125 (12.8)

 ≥80

487 (38.5)

54 (5.5)

Tumor size, mm

 ≤20

638 (50.5)

528 (54.0)

 >20

626 (49.5)

449 (45.9)

 Unknown

0

1 (0.1)

Tumor grade

 Well

272 (21.5)

38 (3.9)

 Moderate

769 (60.8)

544 (55.6)

 Poor

223 (17.6)

356 (36.4)

 Unknown

0

40 (4.1)

PR status

 PR–

240 (19.0)

163 (16.7)

 PR+

971 (76.8)

677 (69.2)

 Unknown

53 (4.2)

138 (14.1)

Surgery type

 Mastectomy

703 (55.6)

401 (41.0)

 Lumpectomy

561 (44.4)

577 (59.0)

Adjuvant endocrine therapy

 Tamoxifen

480 (38.0)

 

 Aromatase inhibitor

190 (15.0)

503 (51.4)

 Sequential

415 (32.8)

475 (48.6)

 Unknown

179 (14.2)

0

Disease recurrence

 Locoregional

26 (2.1)

26 (2.7)

 Distant

83 (6.6)

93 (9.5)

  1. NCR Netherlands Cancer Registry, PR progesterone receptor, TEAM Tamoxifen and Exemestane Adjuvant Multinational trial.