Fig. 5: Comparison of the microbial abundance changes specific to the status of IBD and CMD. | npj Genomic Medicine

Fig. 5: Comparison of the microbial abundance changes specific to the status of IBD and CMD.

From: Gut microbial and human genetic signatures of inflammatory bowel disease increase risk of comorbid mental disorders

Fig. 5: Comparison of the microbial abundance changes specific to the status of IBD and CMD.

Log2-fold changes (LFCs) in microbial abundance were estimated at the various taxonomic levels in a differential abundance analysis between healthy controls and patients with IBD (a), and between CMD-free and CMD-affected IBD patients (b). c The LFCs were then plotted in volcano plots based on their PFDR values. The scatter plot represents phenotype-specific LFCs for genera associated with either IBD or CMD (PFDR < 0.05). Data points highlighted in red with error bars of 95% confidence intervals indicate the genera whose abundance changes were significant in both phenotypes. Their names were provided with the initial of the lowest taxonomic rank that was classified. N.S. not significant.

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