Fig. 6: Interaction of endothelial dysfunction and inflammatory markers with static retinal vessel parameters and LysoGb3 in FD patients with a potential cardiac GLA gene variant. | npj Genomic Medicine

Fig. 6: Interaction of endothelial dysfunction and inflammatory markers with static retinal vessel parameters and LysoGb3 in FD patients with a potential cardiac GLA gene variant.

From: Endothelial dysfunction in Fabry disease: retinal biomarkers link cardiac GLA gene variants with chronic inflammation

Fig. 6

Interaction plots visualize the effect of cardiac gene variants (red line, n = 20) and no cardiac variants (green, dashed line, n = 42) on the correlation between CRAE (a–d), AVR (e), CRVE (f), and LysoGB3 (g) with levels of inflammatory and endothelial dysfunction parameters. MCP1, CXCL10, Rantes and LysoGb3 were log-transformed (all n = 63). Pinteraction displays the interactions between FD patients with a potential cardiac gene variant and laboratory variables calculated in a multivariable linear model. This figure was created with Affinity Publisher (Version 2.5.5).

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