Fig. 2: Evaluation of QLED-based aPDT for killing MDR bacteria. | npj Flexible Electronics

Fig. 2: Evaluation of QLED-based aPDT for killing MDR bacteria.

From: Advancing flexible quantum dot light-emitting diode technology for antimicrobial photodynamic therapy

Fig. 2

A Rigid QLED device with illumination pixels used for aPDT. B, C In-vitro aPDT efficacy of QLEDs against MDR S. aureus (gram-positive) and E. coli (gram-negative) showing significant bacterial reduction with photosensitizer (MB) and QLED light combination (MB + QLED). Asterisks (*) indicate cases where bacterial survival was undetectable. The mean of each treatment group was compared to the control group using a t-test. Statistical significance is shown as follows: NS (not significant), * (P < 0.05), and ** (P < 0.01). D Schematic of an ex-vivo pig skin infection model with a skin burn inoculated with MDR bacteria, including MDR S. aureus (gram-positive) and P. aeruginosa (gram-negative). E Bioluminescence imaging results demonstrating the killing efficacy of QLED-based aPDT in ex-vivo models, comparing untreated, MB-only, light-only, and MB + light treatment groups for MDR S. aureus and P. aeruginosa strains.

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