Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Advertisement

npj Flexible Electronics
  • View all journals
  • Search
  • My Account Login
  • Content Explore content
  • About the journal
  • Publish with us
  • Sign up for alerts
  • RSS feed
  1. nature
  2. npj flexible electronics
  3. articles
  4. article
A wireless implantable sensory ring for continuous airway stent migration tracking
Download PDF
Download PDF
  • Article
  • Open access
  • Published: 14 January 2026

A wireless implantable sensory ring for continuous airway stent migration tracking

  • Ruijian Ge1,
  • Yusheng Wang1,
  • Carlos Negron1,
  • Hanwen Fan2,
  • Fabien Maldonado1,3,
  • Caitlin T. Demarest4,
  • Victoria Simon4,
  • Yuxiao Zhou2 &
  • …
  • Xiaoguang Dong1,5,6,7 

npj Flexible Electronics , Article number:  (2026) Cite this article

  • 894 Accesses

  • 15 Altmetric

  • Metrics details

We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the manuscript will undergo further editing. Please note there may be errors present which affect the content, and all legal disclaimers apply.

Subjects

  • Diseases
  • Engineering
  • Health care
  • Medical research

Abstract

Airway stents play a vital role in managing central airway obstruction (CAO) caused by lung cancer and other pulmonary diseases by providing structural support to collapsed airways and restoring airflow. However, complications such as stent migration often require urgent medical intervention while early monitoring is essential to reduce the risk. Regular monitoring through bronchoscopy requires anesthesia in the hospital, which causes pain and an economic burden on patients. Computed tomography involves risky radiation and lacks the ability to provide continuous, real-time feedback outside of hospital settings. Here we report a fundamental mechanism of wireless tracking based on magnetic field in a wirelessly powered sensory ring integrated on an airway stent. The sensory ring is designed for continuous, real-time monitoring of stent position and orientation. This sensory ring, integrating an on-board magnetic sensor, and a wearable magnetic field generation system, enable accurate localization by detecting the magnetic field generated externally. The sensory ring is powered wirelessly via a charging coil, ensuring long-term operation. Our system achieves tracking accuracy of 0.5 mm and 2.2 degrees, with a temporal resolution of 0.2 Hz. Beyond migration monitoring, the sensor also detects airway deformation, offering the potential to sense pathological changes associated with lung cancer and other pulmonary conditions. By eliminating the need for radiation-based imaging or bronchoscopy, this approach enables safe, long-term surveillance of stent patency and surrounding tissue conditions. The proposed sensing mechanism and platform are also adaptable in other organs, such as the esophagus, for monitoring stent migration and deformation.

Similar content being viewed by others

Prognostic factors and clinical outcomes of stenting on malignant central airway obstruction

Article Open access 21 April 2025

A microsystem for in vivo wireless monitoring of plastic biliary stents using magnetoelastic sensors

Article Open access 31 October 2024

Automatic airway segmentation from computed tomography using robust and efficient 3-D convolutional neural networks

Article Open access 06 August 2021

Data availability

All data is contained within the manuscript and supplementary files.

Code availability

The C++ and MATLAB codes for tracking can be accessed via the link: https://github.com/dong-mrlab/stent_migration.

References

  1. Mudambi, L., Miller, R. & Eapen, G. A. Malignant central airway obstruction. J. Thorac. Dis. 9, S1087–S1110 (2017).

    Google Scholar 

  2. Keshishyan, S. et al. Infections causing central airway obstruction: role of bronchoscopy in diagnosis and management. J. Thorac. Dis. 9, 1707–1724 (2017).

    Google Scholar 

  3. Ernst, A., Feller-Kopman, D., Becker, H. D. & Mehta, A. C. Central airway obstruction. Am. J. Respir. Crit. Care Med. 169, 1278–1297 (2004).

    Google Scholar 

  4. Folch, E. & Keyes, C. Airway stents. Ann. Cardiothorac. Surg. 7, 273–283 (2018).

    Google Scholar 

  5. Bashour, S. I. & Lazarus, D. R. Airway stents in interventional pulmonology. J. Respir. 4, 62–78 (2024).

    Google Scholar 

  6. Sabath, B. F. & Casal, R. F. Airway stenting for central airway obstruction: a review. Mediastinum 7, 18 (2023).

  7. Wang, Z. et al. Utility and safety of airway stenting in airway stenosis after lung transplant: a systematic review. Front. Med. 10, 1061447 (2023).

    Google Scholar 

  8. Mencattelli, M. et al. In vivo molding of airway stents. Adv. Funct. Mater. 31, 2010525 (2021).

    Google Scholar 

  9. Lee, H. J. et al. Airway stent complications: the role of follow-up bronchoscopy as a surveillance method. J. Thorac. Dis. 9, 4651–4659 (2017).

    Google Scholar 

  10. Murgu, S. D. & Colt, H. G. Complications of silicone stent insertion in patients with expiratory central airway collapse. Ann. Thorac. Surg. 84, 1870–1877 (2007).

    Google Scholar 

  11. Zakaluzny, S. A., Lane, J. D. & Mair, E. A. Complications of tracheobronchial airway stents. Otolaryngol.–Head. Neck Surg. 128, 478–488 (2003).

    Google Scholar 

  12. Guibert, N., Saka, H. & Dutau, H. Airway stenting: technological advancements and its role in interventional pulmonology. Respirology 25, 953–962 (2020).

    Google Scholar 

  13. Lin, S.-M. et al. Metallic stent and flexible bronchoscopy without fluoroscopy for acute respiratory failure. Eur. Respir. J. 31, 1019–1023 (2008).

    Google Scholar 

  14. Shang, J. et al. A flexible catheter-based sensor array for upper airway soft tissues pressure monitoring. Nat. Commun. 16, 287 (2025).

    Google Scholar 

  15. Godoy, M. C. B. et al. Multidetector CT evaluation of airway stents: what the radiologist should know. Radiographics 34, 1793–1806 (2014).

    Google Scholar 

  16. Okajima, Y. et al. Luminal plugging on chest CT scan. Chest 158, 121–130 (2020).

    Google Scholar 

  17. Dialani, V. et al. MDCT detection of airway stent complications: comparison with bronchoscopy. Am. J. Roentgenol. 191, 1576–1580 (2008).

    Google Scholar 

  18. Wang, Y., Ge, R. & Dong, | Xiaoguang. Toward wireless implantable robotic systems driven by magnetic field for personalized therapy. Adv. Robot. Res. 202500077 https://doi.org/10.1002/ADRR.202500077 (2025).

  19. Herbert, R., Lim, H.-R., Rigo, B. & Yeo, W.-H. Fully implantable wireless batteryless vascular electronics with printed soft sensors for multiplex sensing of hemodynamics. Sci. Adv. 8, 1175 (2022).

    Google Scholar 

  20. Kwon, K. et al. A battery-less wireless implant for the continuous monitoring of vascular pressure, flow rate and temperature. Nat. Biomed. Eng. 7, 1215–1228 (2023).

    Google Scholar 

  21. Bateman, A. et al. Implantable membrane sensors and long-range wireless electronics for continuous monitoring of stent edge restenosis. ACS Appl. Mater. Interfaces 17, 42781–42790 (2025).

  22. Chen, X., Assadsangabi, B., Hsiang, Y. & Takahata, K. Enabling angioplasty-ready “Smart” stents to detect in-stent restenosis and occlusion. Adv. Sci. 5, 1700560 (2018).

    Google Scholar 

  23. Vishnu, J. & Manivasagam, G. Perspectives on smart stents with sensors: from conventional permanent to novel bioabsorbable smart stent technologies. Med. Devices Sens. 3, e10116 (2020).

    Google Scholar 

  24. Wang, Y. et al. Sensory artificial cilia for in situ monitoring of airway physiological properties. Proc. Natl. Acad. Sci. USA 121, e2412086121 (2024).

    Google Scholar 

  25. Rigo, B. et al. Soft implantable printed bioelectronic system for wireless continuous monitoring of restenosis. Biosens. Bioelectron. 241, 115650 (2023).

    Google Scholar 

  26. Oyunbaatar, N.-E. et al. Implantable self-reporting stents for detecting in-stent restenosis and cardiac functional dynamics. ACS Sens. 8, 4542–4553 (2023).

    Google Scholar 

  27. Yi, Y., Wang, B. & Li, C. Sensors-based monitoring and treatment approaches for in-stent restenosis. J. Biomed. Mater. Res. B Appl. Biomater. 111, 490–498 (2023).

    Google Scholar 

  28. Su, S. et al. A wearable, reconfigurable, and modular magnetic tracking system for wireless capsule robots. IEEE Trans. Ind. Inf. 20, 13600–13611 (2024).

    Google Scholar 

  29. Fu, Y. & Guo, Y.-X. Wearable permanent magnet tracking system for wireless capsule endoscope. IEEE Sens. J. 22, 8113–8122 (2022).

    Google Scholar 

  30. Song, S. et al. Magnetic tracking of wireless capsule endoscope in mobile setup based on differential signals. IEEE Trans. Instrum. Meas. 70, 1–1 (2021).

  31. Son, D., Dong, X. & Sitti, M. A simultaneous calibration method for magnetic robot localization and actuation systems. IEEE Trans. Robot. 35, 343–352 (2019).

    Google Scholar 

  32. Taylor, C. R. et al. Magnetomicrometry. Sci Robot 6, eabg0656 (2021).

  33. Huang, Z. et al. Three-dimensional integrated stretchable electronics. Nat. Electron. 1, 473–480 (2018).

    Google Scholar 

  34. Zhao, Q. et al. Highly stretchable and customizable microneedle electrode arrays for intramuscular electromyography. Sci. Adv. 10, 7202 (2024).

    Google Scholar 

  35. Yin, J., Wang, S., Tat, T. & Chen, J. Motion artefact management for soft bioelectronics. Nat. Rev. Bioeng. 2, 541–558 (2024).

    Google Scholar 

  36. Jin, R. & Jung, B. Magnetic tracking system for heart surgery. IEEE Trans. Biomed. Circuits Syst. 16, 275–286 (2022).

    Google Scholar 

  37. Kim, K. et al. Mucosa-interfacing capsule for in situ sensing the elasticity of biological tissues. Adv. Mater. Technol. 10, 2401487 (2025).

    Google Scholar 

  38. Gleich, B., Schmale, I., Nielsen, T. & Rahmer, J. Miniature magneto-mechanical resonators for wireless tracking and sensing. Science 380, 966–971 (2023).

    Google Scholar 

  39. Taylor, C. R., Abramson, H. G. & Herr, H. M. Low-latency tracking of multiple permanent magnets. IEEE Sens J. 19, 11458–11468 (2019).

    Google Scholar 

  40. Sherman, J. T., Lubkert, J. K., Popovic, R. S. & DiSilvestro, M. R. Characterization of a novel magnetic tracking system. IEEE Trans. Magn. 43, 2725–2727 (2007).

    Google Scholar 

  41. Dai, H., Yang, W., Xia, X., Su, S. & Ma, K. A three-axis magnetic sensor array system for permanent magnet tracking. in Proc. 2016 IEEE International Conference on Multisensor Fusion and Integration for Intelligent Systems (MFI) vol. 0 476–480 (IEEE, 2016).

  42. Franz, A. M. et al. Electromagnetic tracking in medicine—a review of technology, validation, and applications. IEEE Trans. Med. Imaging 33, 1702–1725 (2014).

    Google Scholar 

  43. Fan, X., Dong, X., Karacakol, A. C., Xie, H. & Sitti, M. Reconfigurable multifunctional ferrofluid droplet robots. Proc. Natl. Acad. Sci. USA 117, 27916–27926 (2020).

    Google Scholar 

  44. Wang, Y., Sharma, S., Maldonado, F. & Dong, X. Wirelessly actuated ciliary airway stent for excessive mucus transportation. Adv. Mater. Technol. 8, 2301003 (2023).

    Google Scholar 

  45. Sharma, S. et al. Wireless peristaltic pump for transporting viscous fluids and solid cargos in confined spaces. Adv. Funct. Mater. 34, 2405865 (2024).

    Google Scholar 

Download references

Acknowledgements

We acknowledge funding support from National Institutes of Health under R21EB035200 and from Vanderbilt University.

Author information

Authors and Affiliations

  1. Department of Mechanical Engineering, Vanderbilt University, Nashville, TN, US

    Ruijian Ge, Yusheng Wang, Carlos Negron, Fabien Maldonado & Xiaoguang Dong

  2. Department of Mechanical Engineering, Texas A&M University, College Station, TX, US

    Hanwen Fan & Yuxiao Zhou

  3. Division of Allergy, Pulmonary and Critical Care Medicine, School of Medicine, Vanderbilt University, Nashville, TN, US

    Fabien Maldonado

  4. Department of Thoracic Surgery, Vanderbilt University Medical Center, Nashville, TN, US

    Caitlin T. Demarest & Victoria Simon

  5. Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, US

    Xiaoguang Dong

  6. Vanderbilt Institute for Surgery and Engineering, Vanderbilt University, Nashville, TN, US

    Xiaoguang Dong

  7. Department of Electrical and Computer Engineering, Vanderbilt University, Nashville, TN, US

    Xiaoguang Dong

Authors
  1. Ruijian Ge
    View author publications

    Search author on:PubMed Google Scholar

  2. Yusheng Wang
    View author publications

    Search author on:PubMed Google Scholar

  3. Carlos Negron
    View author publications

    Search author on:PubMed Google Scholar

  4. Hanwen Fan
    View author publications

    Search author on:PubMed Google Scholar

  5. Fabien Maldonado
    View author publications

    Search author on:PubMed Google Scholar

  6. Caitlin T. Demarest
    View author publications

    Search author on:PubMed Google Scholar

  7. Victoria Simon
    View author publications

    Search author on:PubMed Google Scholar

  8. Yuxiao Zhou
    View author publications

    Search author on:PubMed Google Scholar

  9. Xiaoguang Dong
    View author publications

    Search author on:PubMed Google Scholar

Contributions

Conceptualization: X.D. Methodology: X.D., R.G., and Y.W. Investigation: R.G., Y.W., C.N., and H.F. Visualization: R.G., Y.W., and X.D. Supervision: X.D. Writing—original draft: X.D., R.G. Writing—review and editing: X.D., R.G., Y.W., C.D., F.M., V.S., and Y.Z. All authors have read and approved the manuscript. R.G. and Y.W. are equally contributed co-first authors.

Corresponding author

Correspondence to Xiaoguang Dong.

Ethics declarations

Competing interests

Vanderbilt University has filed a provisional patent application related to this work. The authors declare that they have no other competing interests.

Additional information

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary information

Supplementary information

video 1

video 2

video 3

video 4

video 5

Rights and permissions

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Ge, R., Wang, Y., Negron, C. et al. A wireless implantable sensory ring for continuous airway stent migration tracking. npj Flex Electron (2026). https://doi.org/10.1038/s41528-025-00526-0

Download citation

  • Received: 11 September 2025

  • Accepted: 31 December 2025

  • Published: 14 January 2026

  • DOI: https://doi.org/10.1038/s41528-025-00526-0

Share this article

Anyone you share the following link with will be able to read this content:

Sorry, a shareable link is not currently available for this article.

Provided by the Springer Nature SharedIt content-sharing initiative

Download PDF

Advertisement

Explore content

  • Research articles
  • Reviews & Analysis
  • News & Comment
  • Collections
  • Follow us on Twitter
  • Sign up for alerts
  • RSS feed

About the journal

  • Aims & Scope
  • Journal Information
  • Content types
  • About the Editors
  • Contact
  • Open Access
  • Article Processing Charges
  • Editorial policies
  • Journal Metrics
  • About the Partner
  • Calls for Papers

Publish with us

  • For Authors and Referees
  • Language editing services
  • Open access funding
  • Submit manuscript

Search

Advanced search

Quick links

  • Explore articles by subject
  • Find a job
  • Guide to authors
  • Editorial policies

npj Flexible Electronics (npj Flex Electron)

ISSN 2397-4621 (online)

nature.com sitemap

About Nature Portfolio

  • About us
  • Press releases
  • Press office
  • Contact us

Discover content

  • Journals A-Z
  • Articles by subject
  • protocols.io
  • Nature Index

Publishing policies

  • Nature portfolio policies
  • Open access

Author & Researcher services

  • Reprints & permissions
  • Research data
  • Language editing
  • Scientific editing
  • Nature Masterclasses
  • Research Solutions

Libraries & institutions

  • Librarian service & tools
  • Librarian portal
  • Open research
  • Recommend to library

Advertising & partnerships

  • Advertising
  • Partnerships & Services
  • Media kits
  • Branded content

Professional development

  • Nature Awards
  • Nature Careers
  • Nature Conferences

Regional websites

  • Nature Africa
  • Nature China
  • Nature India
  • Nature Japan
  • Nature Middle East
  • Privacy Policy
  • Use of cookies
  • Legal notice
  • Accessibility statement
  • Terms & Conditions
  • Your US state privacy rights
Springer Nature

© 2026 Springer Nature Limited

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing