Fig. 1: Dose-dependent toxicity of rotenone in primary neuronal cultures. | npj Parkinson's Disease

Fig. 1: Dose-dependent toxicity of rotenone in primary neuronal cultures.

From: Rotenone induced acute miRNA alterations in extracellular vesicles produce mitochondrial dysfunction and cell death

Fig. 1: Dose-dependent toxicity of rotenone in primary neuronal cultures.

(i) Primary midbrain neurons and (ii) primary cortical neurons were treated with different doses of rotenone as mentioned above for 24 h, and cell viability was assessed by a MTT cell viability assay at 570 nm and b cell death detection by ELISA at 405 nm. Asterisk (*), (**), and (***) indicates values statistically significant from control; p value <0.05, <0.01, and <0.001 (respectively), SEM of three independent experiments, data were analyzed using one-way ANOVA, followed by Dunnett’s multiple comparisons test.

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