Fig. 5: A53T mice exhibit loss of TH-positive neurons and motor deficits after CUMS treatment. | npj Parkinson's Disease

Fig. 5: A53T mice exhibit loss of TH-positive neurons and motor deficits after CUMS treatment.

From: Chronic stress induces depression-like behaviors and Parkinsonism via upregulating α-synuclein

Fig. 5

a Representative images of SNpc TH-positive neurons and (b) quantification. Scale bar, 100 μm. n = 6 mice per group. c Representative images of striatum TH-positive fibers and (d) quantification. Scale bar, 200 μm. n = 6 mice per group. Performance in the (e) rotarod test and (f) pole test. n = 10 mice per group. Data are shown as mean ± SEM. The data were analyzed by two-way ANOVA followed by Tukey’s post hoc test. The P values are labeled in the diagram. ns not significant, SNpc substantia nigra pars compacta, AOD average optical density.

Back to article page