Table 2 Response of resting and action tremor to treatments: statistical output

From: Resting and action tremor in Parkinson’s disease: pathophysiological insights from long-term STN-DBS

Skillings–Mack test (Q2; p)a

RESTING TREMOR

ACTION TREMOR

7.86; 0.02

13.98; 0.001

Wilcoxon test (Z; p)

L-DOPA vs DBS

L-DOPA vs DBS + L-DOPA

DBS vs DBS + L-DOPA

L-DOPA vs DBS

L-DOPA vs DBS + L-DOPA

DBS vs DBS + L-DOPA

−4.889; <0.001

−0.277; 0.782

−4.077; <0.001

−3.985; <0.001

−5.011; <0.001

−1.877; 0.061

 

RESTING VS ACTION TREMOR

Kruskal–Wallis test (U5; p)a

87.762; <0.001

Mann–Whitney test (U; p)

L-DOPA

20578.5; <0.001

STN-DBS

20765.5; <0.001

STN-DBS + L-DOPA

23106.0; 0.04

  1. DBS deep-brain stimulation.
  2. aAll patients evaluated at baseline (n = 301) underwent assessment under each therapeutic condition (L-Dopa, DBS, and combined DBS + L-Dopa).
  3. Bold values indicate statistical significance.
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