Fig. 6: Jitter plots showing variant distribution (number of variants per patient) in patients and controls.
From: The genetic architecture of Parkinson’s disease on the Island of Crete
a Stratification based on pathogenic/likely pathogenic variants (yellow dots) vs. variants of uncertain significance (blue dots); b stratification based on variants in high-confidence genes (red dots) vs. low-confidence genes (green dots). The overall variant burden of pathogenic/likely pathogenic variants or VUS did not differ significantly between groups when both high- and low-level confidence genes were considered. However, variants in high-confidence genes (both pathogenic/likely pathogenic variants and VUS) were significantly enriched in patients (p-values from Kruskal-Wallis test).
