Table 1 Demographics and characteristics of PD patients and controls in the Cretan PD Cohort
From: The genetic architecture of Parkinson’s disease on the Island of Crete
PD patients (n = 360) | Controls (n = 251) | p-value | |
|---|---|---|---|
Sex (male) | 60.8% | 66.1% | p = 0.211 |
Age (median, range) (y) | 70.0 (35.0–88.6) | 68.7 (42.4–90.0) | p = 0.638 |
Ethnicity (Greek) | 96.9% | 100% | p = 0.0036 |
PD patients | |||
Ethnicity | Greek (n = 348); Albanian (n = 6); Dutch (n = 2); American (n = 1); British (n = 1); Bulgarian (n = 1); Iranian (n = 1) | ||
Origin | Origin from Crete from both sides (n = 311, 86.4%) Origin from the Greek mainland or Anatolia from at least one side (n = 37, 10.3%) Other non-Greek origin (n = 12, 3%) | ||
Age at symptoms onset (median, range) (y) | 60.7 (26.0–86.3) | ||
Age at diagnosis (median, range) (y) | 62.4 (27.0–87.4) | ||
Early-onset (<50 years at PD diagnosis) | 18.3% (n = 66) | ||
Family history (+)a | 28.6% (n = 103) •Vertical (autosomal dominant) pattern: 86.4% (n = 89) •Horizontal (autosomal recessive) pattern: 13.6% (n = 14) | ||
Deceased patients | 16.4% (n = 59) | ||
Disease duration until death (mean ± SD) (y) | 15.3 ± 7.4 | ||
