Table 1 Demographic and clinical characteristics of the study participants
PPMI-Online | Fox Insight | |||
|---|---|---|---|---|
No PD | PD | P value a | PD | |
(n = 10,245) | (n = 5660) | (n = 1929) | ||
Age at sleep report (years), Mean (SD) | 65.8 (7.97) | 69.7 (7.27) | <0.001 | 67.5 (6.87) |
Age at onset of PD (years), Mean (SD) | NA | 65.3 (7.57) | NA | 62.9 (6.96) |
Follow-up since enrollment (months), Mean (SD) | 23.0 (8.58) | 22.2 (8.91) | <0.001 | 68.1 (10.1) |
Sex (Female), No (%) | 6428 (62.7%) | 2367 (41.8%) | <0.001 | 940 (48.7%) |
Race (Non-White), No (%) | 399 (3.9%) | 196 (3.6%) | 0.12 | 38 (2.0%) |
Education b | 17.0 (3.20) | 16.5 (3.56) | <0.001 | 68.3% > = Bachelor’s degree |
Yearly Household Income, No (%) | <0.001 | |||
<$50,000 | 1029 (10.0%) | 707 (12.5%) | 452 (23.4%) | |
$50,000 to $99,999 | 2637 (25.7%) | 1517 (26.8%) | 625 (32.4%) | |
More than $100,000 | 4971 (48.5%) | 2473 (43.7%) | 562 (29.1%) | |
Prefer not to answer | 1331 (13.0%) | 791 (14.0%) | 287 (14.9%) | |
Missing | 277 (2.70%) | 172 (3.0%) | 3 (0.2%) | |
Family history of PD No (%) | 5965 (58.2%) | 1664 (29.4%) | <0.001 | 525 (27.2%) |
RBD1Q | <0.001 | |||
No | 7566 (73.9%) | 2646 (46.7%) | 1141 (59.1%) | |
Yes | 2320 (22.6%) | 2766 (48.9%) | 779 (40.3%) | |
Not sure or Prefer not to answer | 358 (3.5%) | 245 (4.4%) | NA | |
MDS-UPDRS part I, Mean (SD) | 5.26 (3.95) | 8.84 (4.51) | <0.001 | NA |
MDS-UPDRS part II, Mean (SD) | 1.77 (3.49) | 10.5 (7.49) | <0.001 | 10.8 (7.45) |
PDAQ-15, Mean (SD) | 54.6 (6.10) | 51.0 (9.11) | <0.001 | 51.8 (8.98) |
GDS-15, Mean (SD) | 2.41 (2.90) | 3.68 (3.44) | <0.001 | 3.46 (3.37) |
PAS, Mean (SD) | 7.23 (6.74) | 9.44 (7.55) | <0.001 | NA |
ESS, Mean (SD) | 5.95 (3.61) | 7.18 (4.20) | <0.001 | NA |
PDSS2, Mean (SD) | 11.7 (6.89) | 16.5 (8.46) | <0.001 | NA |
