Fig. 4: Gene set enrichment analysis in the whole MSA sample.

Significant biological processes (a), cellular components (b), and tissue cell types (c) enriched in the negatively-weighted genes associated with deep brain atrophy in MSA. Terms are ranked based on the normalized enrichment score; all enriched terms were significant after FDR correction. Only the top 15 terms are shown for visualization purposes. FDR false discovery rate, NES normalized enrichment score.