Table 5 Measurement of clinical features and steps to harmonize between cohorts

From: Prediction of impulse control disorders in Parkinson’s disease through a longitudinal machine learning study

Outcome

PPMI measure

AMSTERDAM UMC measure

Harmonization step

Disease stage

Hoehn & Yahr stage

Modified Hoehn & Yahr stage

We recoded stages 1.5 and 2.5 (from the modified version) to stage 240

PD motor symptom severity

Movement Disorder Society-Unified PD Rating Scale motor score (MDS-UPDRS)

UPDRS part III motor score

We added 7 points to the original UPDRS-III total score41.

Depressive symptoms

Geriatric Depression Scale-15

Beck Depression Inventory

We recoded total scores into four severity classifications (None, Mild, Moderate, Severe)42,43

Anxiety

Trait subscale of the State-Trait Anxiety Inventory

Beck Anxiety Inventory

.We recoded total scores into three severity classifications (None/Minimal, Moderate, Severe/High)44,45

Apathy

MDS-UPDRS part I item 5

UPDRS part I item 4

None

Global cognitive function

Montreal Cognitive Assessment (MoCA)

Mini-Mental State Examination (MMSE)

We converted the MoCA scores to an MMSE score46

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