Table 1 Demographic and clinical characteristics
PD | P valuea | Matched control | P valueb | |||
|---|---|---|---|---|---|---|
Variables | Total | LMM | NMM | |||
No. of participants | 409 | 143 | 266 | — | 2045 | — |
Age, y | 71.1 (9.5) | 74.0 (9.1) | 69.4 (9.2) | <0.001 | 70.8 (7.8) | 0.515 |
Male, % | 214 (52.3%) | 94 (65.7%) | 120 (45.1%) | <0.001 | 1024 (50.1%) | 0.406 |
Age of onset, y | 66.2 (10.1) | 69.3 (10.0) | 64.6 (9.8) | <0.001 | — | — |
Disease duration, y | 4.8 (4.7) | 4.7 (4.8) | 4.8 (4.6) | 0.875 | — | — |
H&Y stage | 2.1 (0.5) | 2.1 (0.6) | 2.1 (0.5) | 0.160 | — | — |
Height, cm | 159.5 (9.7) | 161.7 (8.7) | 158.3 (10.1) | <0.001 | 159.5 (9.1) | 0.969 |
Weight, kg | 61.1 (11.2) | 56.2 (8.5) | 63.8 (11.5) | <0.001 | 61.9 (10.7) | 0.165 |
BMI, kg/m2 | 24.0 (3.7) | 21.6 (3.4) | 25.4 (3.2) | <0.001 | 24.3 (3.3) | 0.075 |
ASMI, kg/m2 | 6.6 (1.1) | 5.8 (0.8) | 7.1 (1.0) | <0.001 | 6.7 (0.9) | 0.044 |
MDS-UPDRS Part 1 score | 8.8 (5.6) | 9.1 (5.2) | 8.7 (5.8) | 0.530 | — | — |
MDS-UPDRS Part 2 score | 6.9 (5.5) | 7.2 (5.5) | 6.8 (5.5) | 0.432 | — | — |
MDS-UPDRS Part 3 score | 25.4 (13.7) | 26.5 (13.8) | 24.7 (13.7) | 0.212 | — | — |
GDS score | 4.6 (4.2) | 4.8 (4.1) | 4.5 (4.3) | 0.416 | — | — |
MoCA score | 20.0 (5.9) | 19.0 (6.0) | 20.5 (5.7) | 0.020 | — | — |
SCOPA-AUT score | 12.1 (7.2) | 12.8 (6.7) | 11.8 (7.4) | 0.193 | — | — |
SBP, mmHg | 142.2 (19.4) | 142.1 (19.9) | 142.3 (19.2) | 0.936 | — | — |
DBP, mmHg | 80.0 (10.9) | 79.7 (11.3) | 80.2 (10.7) | 0.602 | — | — |
HR, beats/min | 71.8 (11.5) | 72.2 (11.7) | 71.7 (11.4) | 0.819 | — | — |
