Table 2 Primary, secondary, and exploratory outcomes in patients with Parkinson’s disease

From: Prevalence of low muscle mass and its association with orthostatic hypotension and related symptoms in Parkinson’s disease

 

LMM (n = 141)

NMM (n = 264)

P value

Primary outcome

OH, %

66 (46.8%)

102 (38.6%)

0.412

Secondary outcomes

Systolic OH, %

37 (26.2%)

47 (17.8%)

0.359

Diastolic OH, %

36 (25.5%)

39 (14.8%)

0.064

Exploratory outcomes

SBP change at 30 sec after standing, mmHg

−18.7 (1.7)

−13.0 (1.1)

0.020

DBP change at 30 sec after standing, mmHg

−7.8 (1.1)

−4.2 (0.6)

0.012a

SBP change at 1 min after standing, mmHg

−18.8 (1.8)

−15.1 (1.1)

0.312

DBP change at 1 min after standing, mmHg

−8.0 (1.1)

−5.4 (0.7)

0.217

SBP change at 3 min after standing, mmHg

−17.1 (1.8)

−14.5 (1.1)

0.330

DBP change at 3 min after standing, mmHg

−7.7 (1.1)

−6.3 (0.7)

0.464

SBP change at 5 min after standing, mmHg

−18.2 (2.1)

−14.5 (1.4)

0.225

DBP change at 5 min after standing, mmHg

−8.1 (1.2)

−6.3 (0.8)

0.369

  1. Data are shown as n (%) or the mean (standard deviation).
  2. DBP diastolic blood pressure, LMM low muscle mass, NMM normal muscle mass, SBP systolic blood pressure, OH orthostatic hypotension.
  3. aThe statistical significance remained after post-hoc Bonferroni corrections.