Fig. 1

Clinically important deteriorations (CID): glycopyrronium versus tiotropium subgroup analysis. Forest plot depicting the results of a subgroup analysis which assessed the risk of experiencing a clinically important deterioration with glycopyrronium (GLY; n = 1859) treatment compared with tiotropium (TIO; n = 1077), based on gender, age, smoking status, exacerbation history, inhaled corticosteroid (ICS) use, baseline St. George’s Respiratory Questionnaire (SGRQ), Baseline Dyspnea Index (BDI) score, COPD severity or blood eosinophil levels. Hazard ratios ±95% confidence intervals (CI) are shown