Table 6 Logistic regression model for variables predicting frequent exacerbations (by co-existing COPD diagnosis status)

From: Insights into frequent asthma exacerbations from a primary care perspective and the implications of UK National Review of Asthma Deaths recommendations

 

With co-existing COPD

Without co-existing COPD

p value for interaction

 

Odds ratio (95% CI); p value

Odds ratio (95% CI); p value

 

Age (per 5 years)

0.94 (0.82, 1.06); p = 0.305

1.09 (1.03, 1.16); p = 0.003

0.029

Gender (male)

0.86 (0.47, 1.57); p = 0.629

0.56 (0.37, 0.85); p = 0.006

0.238

BTS step (1/2/unclear)

BTS step (4/5)

0.37 (0.10, 1.33); p = 0.129

2.60 (1.39, 4.88); p = 0.003

0.29 (0.18, 0.48); p < 0.001

2.94 (1.87, 4.63); p < 0.001

0.8635

SABA over-use (yes)

2.75 (1.26, 6.02); p = 0.011

1.89 (0.94, 3.84); p = 0.076

0.485

  1. COPD chronic obstructive pulmonary disease, BTS British Thoracic Society, ICS inhaled crticosteroids, SABA short-acting β2-antagonist
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