Table 1 Characteristics of patients with primary outcome (n = 58).
From: Pragmatic trial on inhaled corticosteroid withdrawal in patients with COPD in general practice
na | ||
|---|---|---|
Age, years (mean) | 58 | 67.1 (SD 10.3) |
Males (n, %) | 58 | 29 (50.0) |
Education level (n, %) | ||
Low | 37 (63.8) | |
Medium | 12 (20.7) | |
High | 7 (12.1) | |
Unknown | 2 (3.4) | |
Smoking history (n, %) | 58 | |
Never smoked | 3 (5.2) | |
Previous smoker | 32 (55.2) | |
Current smoker | 23 (39,7) | |
Packyears (n, %) | 52 | |
≤25 packyears | 25 (43.1) | |
>25 packyears | 27 (46.6) | |
Inhaled corticosteroid inhaler (n, %) | 58 | |
Single therapy | 7 (12.1) | |
Combihaler with long-acting bronchodilator | 51 (87.9) | |
Type of inhaled corticosteroids (n, %) | 58 | |
Fluticasone proprionate | 32 (55.2) | |
Budesonide | 22 (37.9) | |
Beclometasone | 4 (6.9) | |
Other medication used before the start (n, %) | 58 | |
None (only ICS) | 2 (3.4) | |
SABA | 1 (1.7) | |
LABA | 22 (37.9) | |
SABA + LABA | 3 (5.2) | |
SAMA + LABA | 4 (6.9) | |
LABA + LAMA | 19 (34.5) | |
LABA + LAMA + SABA | 7 (12.1) | |
MRC score | 57 | |
1 | 28 (49.1) | |
2 | 20 (35.1) | |
3 | 7 (12.3) | |
4 | 2 (3.5) | |
5 | 0 | |
Asthma characteristics (n, %) | ||
Diagnosed with asthma in the past | 58 | 17 (29.3) |
Asthma diagnosed in first-line family member | 58 | 21 (36.2) |
Hay fever | 58 | 9 (15.5) |
Atopic eczema | 58 | 11 (19.0) |
Relevant allergy (inhalation allergens) | 57 | 6 (10.5) |
Lung function (mean) | ||
Airflow obstruction (FEV1/FVC ratio) | 51 | 0.57 (SD 0.10) |
FEV1 % predictedb | 56 | 64.5 (SD 13.4) |
Reversibility FEV1 ≥12% (n) | 22 | 2 |
Comorbidity (n, %) | 58c | |
Fatigue | 13 (22.4) | |
Diabetes | 7 (12.1) | |
Musculoskeletal disorders like low back pain | 16 (27.6) | |
Osteoarthritis | 17 (29.3) | |
Cancer | 2 (3.4) | |
Heart diseases | 8 (13.8) | |
Other diseases | 10 (17.2) | |
