Table 1 Study selection criteria.

From: Daytime symptoms of chronic obstructive pulmonary disease: a systematic review

 

Criteriaa

Patient

• Adult patients (>40 years) of any gender or race, with a diagnosis of COPD (any disease severity) and having daytime COPD symptoms

• Studies enrolling a mixed population of patients experiencing daytime and night-time symptoms were only included if subgroup data for patients with daytime symptoms were available

Intervention

• No selection criteria

Comparator

• No selection criteria

Outcome

• Primary outcomes of interest included: prevalence of daytime COPD symptoms; relative bothersomeness/troublesomeness or intensity of symptoms; how the prevalence and bothersomeness/troublesomeness or intensity fluctuates throughout the day; relationship between daytime COPD symptoms and other outcomes, such as activities of daily living, health status, quality of life, and exacerbations; types of interventions used to treat daytime symptoms, including pharmacotherapy; and measures and tools used to assess daytime COPD symptoms

Study design

• All studies reporting any data on daytime COPD symptoms (e.g., multi- and single-center randomized controlled trials, nonrandomized trials, single-arm clinical trials, and real-world and observational studies)

• Studies with full-text publications available only in languages other than English were excluded

  1. COPD chronic obstructive pulmonary disease.
  2. aCriteria were in line with Patient, Intervention, Comparator, Outcomes and Study Design (PICOS).