Table 1 Characteristic of the sample population.

From: Association between chronic obstructive pulmonary disease and ventricular arrhythmia: a nationwide population-based cohort study

	Whole cohort (n = 143,676)		Non-COPD (n = 71,838)		COPD (n = 71,838)		P*
	n	%	n	%	n	%	P*
Age, years (mean ± SD)	57.66 ± 16.61		57.66 ± 16.61		57.67 ± 16.61		0.954
20–64	90,018	62.65	45,022	62.67	44,996	62.64	0.990
65–74	30,354	21.13	15,171	21.12	15,183	21.14
≥75	23,304	16.22	11,645	16.21	11,659	16.23
Sex
Female	65,886	45.86	32,943	45.86	32,943	45.86	0.998
Male	77,790	54.14	38,895	54.14	38,895	54.14	0.998
CHA2DS2-VASc score
0	30,849	21.47	17,183	23.92	13666	19.02	<0.001
1	42,353	29.48	22,377	31.15	19,976	27.81
2 or 3	39,298	27.35	18,952	26.38	20,346	28.32
≥4	31,176	21.70	13,326	18.55	17,850	24.85
ORBIT score
0–2	107,706	74.96	57,649	80.25	50,057	69.68	<0.001
3	20,416	14.21	8109	11.29	12,307	17.13
≥4	15,554	10.83	6080	8.46	9474	13.19
Comorbidities
Heart Failure	8049	5.60	2705	3.77	5344	7.44	<0.001
AMI	1684	1.17	691	0.96	993	1.38	<0.001
Stroke	19,976	13.90	7871	10.96	12,105	16.85	<0.001
Ischemic heart disease	29,560	20.57	11,642	16.21	17,918	24.94	<0.001
Angina	10,460	7.28	4061	5.65	6399	8.91	<0.001
Peripheral vascular disease	9665	6.73	3945	5.49	5720	7.96	<0.001
Hypertension	55,984	38.97	24,543	34.16	31,441	43.77	<0.001
Diabetes	28,270	19.68	12,371	17.22	15,899	22.13	<0.001
Depression	4708	3.28	1663	2.31	3045	4.24	<0.001
Renal failure	13,247	9.22	5443	7.58	7804	10.86	<0.001
Chronic liver disease	32,760	22.80	13,273	18.48	19,487	27.13	<0.001
Dementia	4303	2.99	1466	2.04	2837	3.95	<0.001
Medication use
Aspirin	39,849	27.74	16,244	22.61	23,605	32.86	<0.001
Statin	32,525	22.64	14,394	20.04	18,131	25.24	<0.001
RAASi	52,914	36.83	22,684	31.58	30,230	42.08	<0.001
Class 1 antiarrhythmic drug	2715	1.89	912	1.27	1803	2.51	<0.001
Class 2 antiarrhythmic drug	34,419	23.96	14,948	20.81	19,471	27.10	<0.001
Class 3 antiarrhythmic drug	5277	3.67	1626	2.26	3651	5.08	<0.001
Class 4 antiarrhythmic drug	16,339	11.37	4659	6.49	11,680	16.26	<0.001
Level of urbanization
Urban	106,310	73.99	53,614	74.63	52,696	73.35	<0.001
Suburban	25,780	17.94	12,720	17.71	13,060	18.18
Rural	11,586	8.06	5504	7.66	6082	8.47
Monthly income (US$)
0	11,052	7.69	5969	8.31	5083	7.08	<0.001
0.03–700	42,830	29.81	20,791	28.94	22,039	30.68
700–1100	47,714	33.21	23,798	33.13	23,916	33.29
≥1100	42,080	29.29	21,280	29.62	20,800	28.95

AMI acute myocardial infarction, COPD chronic obstructive pulmonary disease, RAASi renin–angiotensin–aldosterone system inhibitor.
*The chi-squared test for categorical variables, and t-test for continuous variable, two-tailed p value.

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Table 1 Characteristic of the sample population.

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