Table 3 Twenty most frequent comorbidities among GP patients and 10 most frequent comorbidities among pulmonology patients using chronic comorbid conditions (CCC) over the three index periods (5 years before, ±5 years during the index date, and 5 years after).

From: Age- and gender-based comorbidity categories in general practitioner and pulmonology patients with COPD

GP patients comorbidity scores, mean (SD)

Index age group

Age < 45: n = 32

45 ≤ Age < 65: n = 218

Age ≥ 65: n = 182

Chronic comorbid conditions

15.13 (8.19)

14.29 (9.09)

16.12 (9.01)

Elixhauser

5.56 (3.42)

5.96 (4.23)

6.22 (3.84)

Elixhauser-vW Index

12.81 (10.47)

14.69 (14.13)

15.92 (12.72)

20 most frequent comorbidities among GP patients (%)

Disease categories

Total

Before

Index period

After

Disease categories

Total

Before

Index period

After

Disease categories

Total

Before

Index period

After

Dorsopathies

81.3

40.6

31.3

9.4

Hypertension

71.1

18.3

38.5

14.2

Hypertension

81.3

31.9

43.4

6.0

Peripheral neuropathy

78.1

0

31.3

46.9

Peripheral neuropathy

66.5

37.6

23.4

5.5

Peripheral neuropathy

70.9

41.2

24.2

5.5

Neurotic, stress-related & somatoform d.a

71.9

25.0

40.6

6.3

Other musculoskeletal & joint d

62.4

27.1

27.1

8.3

Dorsopathies

68.7

43.4

20.3

4.9

Other musculoskeletal & joint d.

68.8

15.6

31.3

21.9

Dorsopathies

61.0

34.9

22.0

4.1

Other musculoskeletal & joint d.

68.7

35.7

28.6

4.4

Esophagus, stomach & duodenum d.

65.6

6.3

50.0

9.4

Esophagus, stomach & duodenum d.

52.8

20.2

26.1

6.4

Osteoarthritis & other degenerative joint d.

62.6

24.7

31.3

6.6

Ear, nose, throat d.

65.6

18.8

37.5

9.4

Neurotic, stress-related & somatoform d.

49.5

21.6

20.6

7.3

Ischemic heart d.

60.4

29.7

24.2

6.6

Depression & mood d.

62.5

9.4

43.8

9.4

Dyslipidemia

47.7

19.7

22.0

6.0

Esophagus, stomach & duodenum d

56.0

19.2

27.5

9.3

Dyslipidemia

59.4

25.0

21.9

12.5

Ischemic heart disease

46.3

17.0

17.9

11.5

Inflammatory Arthropathies

50.0

27.5

19.2

3.3

Thyroid d.

53.1

9.4

28.1

15.6

Osteoarthritis & other degenerative joint d.

44.0

11.9

22.0

10.1

Dyslipidemia

50.0

25.8

22.0

2.2

Other metabolic d.

53.1

21.9

25.0

6.3

Other metabolic d.

43.6

21.6

15.6

6.4

Other metabolic d.

48.9

26.9

20.3

1.6

Asthma

53.1

18.8

18.8

15.6

Thyroid d.

42.7

11.9

21.6

9.2

Heart failure

44.5

12.6

25.8

6.0

Allergy

50.0

18.8

25.0

6.3

Asthma

40.8

7.8

20.6

12.4

Neurotic, stress-related & somatoform d.

44.5

21.4

18.7

4.4

Hypertension

50.0

9.4

21.9

18.8

Diabetes

40.8

15.1

21.1

4.6

Venous & lymphatic d.

42.9

17.0

18.1

7.7

Inflammatory Arthropathies

46.9

21.9

21.9

3.1

Inflammatory Arthropathies

40.8

22.0

16.1

2.8

Diabetes

39.0

14.3

20.3

4.4

Anemia

46.9

25.0

15.6

6.3

Allergy

39.4

13.8

17.4

8.3

Depression & mood d.

39.0

14.3

17.0

7.7

Blood & blood forming organ d.

43.8

9.4

12.5

21.9

Ear, nose, throat d.

38.1

10.6

18.8

8.7

Colitis & related d.

38.5

13.7

14.8

9.9

Osteoarthritis & other degenerative joint d.

43.8

6.3

15.6

21.9

Blood & blood forming organ d.

37.6

5.0

14.2

18.3

Allergy

37.4

12.1

22.5

2.7

Diabetes

40.6

12.5

18.8

9.4

Colitis & related d.

36.2

10.1

15.6

10.6

Cerebrovascular disease

36.3

11.5

16.5

8.2

Colitis & related d.

37.5

6.3

12.5

18.8

Depression & mood d.

35.8

12.4

17.0

6.4

Thyroid d.

36.3

10.4

22.5

3.3

Venous & lymphatic d.

34.4

3.1

12.5

18.8

Venous & lymphatic d.

35.3

9.6

16.5

9.2

Cataract & other lens d.

36.3

6.0

22.0

8.2

Pulmonology patients comorbidity scores, mean (SD)

Index age group

Age < 45: n = 49

45 ≤ Age < 65: n = 260

Age ≥ 65: n = 239

Chronic comorbid conditions

3.37 (1.40)

3.18 (1.73)

3.03 (1.53)

Elixhauser

1.55 (.82)

1.67 (1.14)

1.81 (1.08)

Elixhauser-vW Index **

3.24 (3.43)

3.68 (3.01)

4.60 (3.4)

10 most frequent comorbidities among pulmonology patients, %

Disease categories

Total

Before

Index period

After

Disease categories

Total

Before

Index period

After

Disease categories

Total

Before

Index period

After

Asthma

51.0

30.6

16.3

4.1

(COPD), emphysema, chronic bronchitis

60.8

26.2

28.5

6.2

(COPD), emphysema, chronic bronchitis

61.5

37.2

21.3

2.9

(COPD), emphysema, chronic bronchitis b

49.0

26.5

14.3

8.2

Sleep disorders

36.2

11.5

13.5

11.2

Hypertension

44.4

4.6

22.6

17.2

Allergy

38.8

20.4

10.2

8.2

Other respiratory d.

33.5

9.2

8.1

16.2

Other respiratory d.

38.1

11.7

14.6

11.7

Sleep disorders

32.7

10.2

10.2

12.2

Hypertension

32.7

0.8

15.4

16.5

Sleep disorders

27.2

11.3

10.5

5.4

Other respiratory d.

30.6

22.4

4.10

4.1

Asthma

31.2

21.2

6.9

3.1

Asthma

26.0

18.0

5.9

2.1

Other psychiatric & behavioral d.

24.5

2.0

14.3

8.2

Allergy

17.0

7.7

5

4.2

Ischemic heart disease

21.8

2.5

7.9

11.3

Obesity

22.5

0

4.1

18.4

Obesity

15.0

1.2

5

8.8

Allergy

10.0

7.5

2.1

0.4

Hypertension

20.4

0

6.1

14.3

Other psychiatric & behavioral d

13.1

1.5

9.2

2.3

Diabetes

10.0

0

4.2

5.9

Chronic infectious d.

12.2

0

4.1

8.2

Ischemic heart disease

12.3

0.8

2.7

8.8

Obesity

7.5

1.7

3.8

2.1

Esophagus, stomach, & duodenum d.

8.2

2.0

2.0

4.1

Diabetes

8.1

1.2

1.2

5.8

Other psychiatric & behavioral d.

7.1

0.4

5.4

1.3

  1. **Three index age group difference significant at p < 0.01 according to ANOVA.
  2. ad.= diseases.
  3. b(COPD), emphysema, chronic bronchitis—frequency is based on the data excluding J44 diagnosis.