Table 1 Participants physical and clinical characteristics.

From: The Timed Up and Go test predicts frailty in patients with COPD

 

COPD (n = 520)

Control (n = 150)

P

Gender male: female

270:250

76:74

0.451

Age (years)

66.1 ± 7.6

65 ± 7.4

0.109

FEV1/FVC (%)

0.53 ± 0.11

0.78 ± 0.05

0.001

FEV1 (% predicted)

58 ± 19

105 ± 14

0.001

FVC (% predicted)

87 ± 21

109 ± 15

0.001

Smoking (pack years)

41 ± 25

22 ± 18

0.001

BMI (kg/m2)

28.0 ± 5.5

28.1 ± 4.1

0.951

Waist circumference (cm)

99.6 ± 15.0

94.7 ± 10.2

0.001

Handgrip (kg)

27.1 ± 9.7

31.3 ± 10.3

0.001

TUG (sec)

11.5 ± 4

8.3 ± 1.2

0.001

CGA total

9 (6–13)

2.25 (1–4)

0.001

Frailty index

0.16 ± 0.08

0.05 ± 0.03

0.001

mMRC

2.0 ± 1

-

-

SGRQ Total

53 (36–68)

-

-

CAT score

21 (14–27)

-

-

  1. All data mean ± SD or Median (IQR), #=Geometric mean, - not assessed.
  2. P < 0.05 significant difference between patients with COPD and controls
  3. BMI body mass index; CAT COPD assessment test; CGA comprehensive geriatric assessment; FEV1 forced expiratory volume in 1 sec; FFMI fat-free mass index; FVC forced vital capacity; mMRC modified Medical Research Council; SGRQ St George’s Respiratory Questionnaire; TUG Timed Up and Go.