Table 1 Physical characterization data of PE-S4 HDL NP and PE-O4 HDL NP in comparison to native HDL2

From: A novel therapy to ameliorate nitrogen mustard-induced limbal stem cell deficiency using lipoprotein-like nanoparticles

 

PE-S4 HDL NP*

PE-O4 HDL NP*

Native HDL2

Hydrodynamic Diameter (nm)

12.80 ± 1.20

14.43 ± 1.79

11.22 ± 1.12

Polydispersity Index

0.459 ± 0.017

0.467 ± 0.123

0.641 ± 0.099

Diameter from TEM (nm)

13.09 ± 3.42

11.49 ± 4.16

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Zeta Potential (mV)

−19.83 ± 2.03

−18.90 ± 1.81

Negative

Phospholipid/ApoA-I

31.50 ± 5.83

32.03 ± 7.19

45.87 ± 7.08

Alpha-Helix (%)

90.2

92.0

71.0