Fig. 3: Acomys regenerative response to whisker pad skin wound.

A An external image of Acomys whisker pad, they only have 4 whiskers in row A and 9 whiskers in rows D and E (see Supplementary Fig. 2) B external image of Acomys whisker pad after wounding the 2nd column of whiskers to the most anterior whiskers in each row (see Supplementary Fig. 1), C external image of Acomys whisker pad 24 dpi. Regenerating whisker follicles are marked with an asterisk, emerging from the wound bed, while a cluster of regenerating pelage hair follicles is marked with an arrow. D Trichrome stain of whisker pad skin 10 dpi, with whisker follicle induction in the skin. E Trichrome stain of whisker pad skin 14 dpi, with pelage hair follicle induction in the skin. F Trichrome stain of whisker pad skin 14 dpi, with follicular condensations in the skin, outlined in dotted line, an uninjured follicle is to the right labeled with “uf,” and yellow arrows point to regenerating pelage hair follicles. G trichrome stain of whisker pad skin 21 dpi, again the regenerating whisker follicle is outlined, the uninjured whisker follicle is labeled with “uf”, and yellow arrows point to regenerating hair follicles. G trichrome stain of horizontal section parallel with skin 44 dpi with three regenerated follicles in a row, showing the regenerated muscle with disorganized matrix on either side of the regenerated row. Scale bars in (D–H) represent 250 µM.