Fig. 7: Differential regulation of cytokines post-injury between strains. | npj Regenerative Medicine

Fig. 7: Differential regulation of cytokines post-injury between strains.

From: Prx1+ progenitors give rise to new articular cartilage when conditions are permissive for endogenous regeneration

Fig. 7: Differential regulation of cytokines post-injury between strains.

A Luminex assay measuring 32 cytokines was undertaken on serum in both strains (A). The 2 columns that are highlighted in red dashed boxes indicate timepoints where a number of differences were observed. The white vertical dashed box represents differences in Ccl2 expression between strains. Graphical representation of the experimental design (B). Changes in serum Ccl2 levels over time and between strains (C). Quantification of Ccl2 mRNA expression in CD38+, CD206+ and GFP+ cells isolated from the synovium of both strains over time (D). *=p < 0.05, **=p < 0.01, ***=p < 0.001.

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