Fig. 2: Chronic wounds exhibit perturbation in levels and localization of numerous lipid species. | npj Regenerative Medicine

Fig. 2: Chronic wounds exhibit perturbation in levels and localization of numerous lipid species.

From: Scaffolds with spatiotemporally controlled growth factor delivery and cyclodextrin-enabled antagonism of growth factor receptor sequestration promote cutaneous wound healing

Fig. 2

Time of flight secondary ion mass spectrometry (ToF-SIMS) was used to spatially map lipid species in a healed acute wound, and b non-healing chronic wound with corresponding horizontal and vertical profiles for each lipid category (n = 3 biological specimens form independent donors). c Quantification of lipid species identified by ToF-SIMS using peak areas normalized to total ion current (n = 4 samples plotted as means with error bars corresponding to standard deviation, ****p < 0.0001, One-way Analysis of Variance followed by Tukey’s HSD). (AW Acute wound, CW Chronic wound).

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