Fig. 3: P2RX7 protein expression detected by N-terminus directed antibody (Ab2).
From: Altered purinergic receptor expression in the frontal cortex in schizophrenia
A There was no significant difference in P2RX7-B 60 kDa bands protein expression in SCZ subjects compared to CTL. B There was no significant difference in P2RX7-B protein expression at 60 kDa band using Ab2 in SCZ subjects “on” vs. “off” antipsychotic medications. C Relative expression (% control) of P2RX7-A 60 kDa in female (white bars) and male (black bars) SCZ subjects. Data presented as mean ± SEM. D Representative images of P2RX7 immunoblot using N-terminus directed antibody. SCZ and CTL samples were run in duplicate for each subject. VCP protein control is expressed approximately 100 kDa. Data presented as mean, blots were analyzed by Student’s t test, n = 19–22/group. DLPFC dorsolateral prefrontal cortex, SCZ schizophrenia, CTL non-psychiatrically ill controls, VCP valosin containing protein.
