Table 2 Correlations between ICI and clinical characteristics in SZ group.

From: Reduction of intracortical inhibition (ICI) correlates with cognitive performance and psychopathology symptoms in schizophrenia

Characteristics

FEDN SZ (N = 46)

Medicated SZ (N = 84)

SICI r

LICI r

SICI r

LICI r

Illness course (years)

−0.121

−0.157

−0.024

−0.134

Chlorpromazine equivalent dose (Mg)

NA

NA

−0.007

−0.162

PANSS

Positive subscore

−0.418#

−0.320

−0.183

−0.181

Negative subscore

−0.334

−0.338

−0.218

−0.075

General psychopathology subscore

−0.320

−0.330

−0.289#

−0.254

Total score

−0.353

−0.357

−0.279#

−0.192

MCCB

Speed of processing

0.548##

0.328

0.510##

0.204

Working memory

0.593##

0.146

0.321#

0.029

Verbal learning

0.409#

0.164

0.267

0.061

Visual learning

0.360

0.232

0.215

0.160

Reasoning and problem-solving

0.497##

0.143

0.200

0.109

Social cognition

0.043

0.033

0.163

0.192

  1. Partial Spearman correlation analysis was used to analyze correlations between characteristics. Significant correlations are highlighted in bold. The hashtag indicates a significant correlation between ICI and clinical characteristics in FEDN SZ and medicated SZ, after Bonferroni correction (#pBonferroni < 0.05; ##pBonferroni < 0.01).
  2. FEDN first-episode drug-naïve, SZ schizophrenia, NA not available, SICI short-interval intracortical inhibition, LICI long-interval intracortical inhibition, PANSS Positive and Negative Syndrome Scale, MCCB MATRICS Consensus Cognitive Battery.
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