Table 2 Clusters of different cortical morphological measures associated with the positive formal thought disorder dimension.

Max.	No. Vtx. Max.	Size (mm²)	MNI (X)	MNI (Y)	MNI (Z)	CWP	CWP (Low)	CWP (High)	No. Vtxs.	Weight Vtx.	Brain regions
Left cortical volume – No significant clusters
Right cortical volume
−4.160	28,459	1696	16	−94	−10	0.0001*	0	0.0002	2369	−4364	Cuneus, calcarine sulcus, occipital pole
−3.332	31,390	755	17	−88	19	0.0475	0.0448	0.0502	1000	−1902	Occipital pole, SOG
Left cortical surface area
−2.578	31,675	1270	−8	−49	14	0.0031*	0.0024	0.0038	2732	−4742	LingG, calcarine sulcus, ventral PCC
4.558	18,380	1191	−60	−51	17	0.0047*	0.0038	0.0056	2626	6062	STS, planum temporale, SupraMG, AngG
Right cortical surface area
−3.043	101,252	1695	16	−90	19	0.0001*	0	0.0002	2406	−4493	Occipital pole, SOG, cuneus
Left cortical thickness
−2.823	9559	754	−30	−68	25	0.0249	0.0229	0.0269	1278	−2240	Occipital pole, MOG, SOS
Right cortical thickness – No significant clusters
Left local gyrification index
2.945	73,392	5522	−52	21	18	0.0001*	0	0.0002	12,768	23,527	STG, HG, insula, SubCG, CS, opercular/triangular IFG, IFS, MFG
2.804	54,841	5127	−39	4	44	0.0001*	0	0.0002	12,062	21,629	MFG, PreCG, CS, PostCG, PostCS, AngG, SupraMG
Right local gyrification index
4.001	75,834	6227	51	−24	−13	0.0001*	0	0.0002	13,896	25,277	MTG, STS, STG, HG, insula, SubCG, opercular/triangular IFG, IFS
2.332	103,579	2165	40	−2	44	0.0001*	0	0.0002	4740	7699	MFG, PreCG, CS, PostCG, PostCS

Clusters represent partial correlations corrected for sex, age, negative formal thought disorder dimension, scanner, and corresponding global measures as well as corrected for multiple comparisons using Monte Carlo simulations of the cluster size. Clusters are visualized in Fig. 1.
*p-value surviving Bonferroni correction for the four different measures (p < 0.0125). AngG angular gyrus, CWP cluster-wise p-value, CWP Low and CWP High, 90% confidence interval for CWP, CS central sulcus, HG Heschl’s gyrus, IFG inferior frontal gyrus, IFS inferior frontal sulcus, LingG lingual gyrus, Max. maximum –log10(p-value) in the cluster (positive/negative values represent positive/negative correlations), MFG middle frontal gyrus, MNI (XYZ) the Montreal Neurological Institute coordinates of the maximum, MOG middle occipital gyrus, MTG middle temporal gyrus, No. Vtx. Max. vertex number at the maximum, No. Vtxs. number of cluster vertices, PCC posterior cingulate cortex, PostCG postcentral gyrus, PostCS postcentral sulcus, PreCG precentral gyrus, Size cluster size in mm², SOG superior occipital gyrus, SOS superior occipital sulcus, STG superior temporal gyrus, STS superior temporal sulcus, SubCG subcentral gyrus, SupraMG supramarginal gyrus, Vtx. vertex, Vtxs. vertices, Weight Vtx. weight of cluster (size x intensity).

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