Table 2 Baseline characteristics per comorbidity cluster.

Female

1756 (47.50)

1342 (46.60)

21 (53.85)

273 (47.64)

120 (58.54)

11.59^a

Male

1941 (52.50)

1538 (53.40)

18 (46.15)

300 (52.36)

85 (41.46)

Married

2296 (62.10)

1836 (63.75)

25 (64.10)

344 (60.03)

91 (44.39)

37.71^a

Single

1117 (30.21)

827 (28.72)

8 (20.51)

188 (32.81)

94 (45.85)

Divorced/Widowed

284 (7.68)

217 (7.53)

6 (15.38)

41 (7.16)

20 (9.76)

Blue-Collar

3084 (83.42)

2428 (84.31)

31 (79.49)

453 (79.06)

172 (83.90)

–^b

White-Collar

264 (7.14)

201 (6.98)

4 (10.26)

47 (8.20)

12 (5.85)

Unemployed

244 (6.60)

178 (6.18)

2 (5.13)

47 (8.20)

17 (8.29)

Retired

105 (2.84)

73 (2.53)

2 (5.13)

26 (4.54)

4 (1.95)

≤25

469 (12.69)

375 (13.02)

1 (2.56)

59 (10.30)

34 (16.59)

–^b

26–39

1142 (30.89)

901 (31.28)

3 (7.69)

167 (29.14)

71 (34.63)

40–59

1753 (47.42)

1365 (47.40)

17 (43.59)

280 (48.87)

91 (44.39)

≥60

333 (9.01)

239 (8.30)

18 (46.15)

67 (11.69)

9 (4.39)

Minority

696 (18.83)

571 (19.83)

7 (17.95)

98 (17.10)

20 (9.76)

14.05^a

Han

3001 (81.17)

2309 (80.17)

32 (82.05)

475 (82.90)

185 (90.24)

Primary and below

1959 (52.99)

1552 (53.89)

10 (25.64)

294 (51.31)

103 (50.24)

–^b

Secondary School

1493 (40.38)

1140 (39.58)

25 (64.10)

239 (41.71)

89 (43.41)

Higher Education

245 (6.63)

188 (6.53)

4 (10.26)

40 (6.98)

13 (6.34)

Rural Residents (Insurance)

902 (24.40)

901 (31.28)

0 (0)

1 (0.17)

0 (0)

–^b

Urban And Rural Residents (Insurance)

2711 (73.33)

1907 (66.22)

38 (97.44)

566 (98.78)

200 (97.56)

Self-Pay

84 (2.27)

72 (2.50)

1 (2.56)

6 (1.05)

5 (2.44)

1

1852 (50.09)

1485 (51.56)

17 (43.59)

249 (43.46)

101 (49.27)

18.62^a

1–2

1110 (30.02)

856 (29.72)

15 (38.46)

183 (31.94)

56 (27.32)

≥3

735 (19.88)

539 (18.72)

7 (17.95)

141 (24.61)

48 (23.41)

Length of hospital stay, day

53.00 (28.00, 64.00)

54.00 (29.00, 63.00)

50.00 (26.50, 54.00)

51.00 (28.00, 65.00)

53.00 (29.00, 76.00)

4.50^c

AB

317 (8.57)

248 (8.61)

3 (7.69)

47 (8.20)

19 (9.27)

–^b

A

1073 (29.02)

864 (30.00)

4 (10.26)

140 (24.43)

65 (31.71)

B

809 (21.88)

652 (22.64)

5 (12.82)

116 (20.24)

36 (17.56)

O

987 (26.70)

770 (26.74)

4 (10.26)

142 (24.78)

71 (34.63)

Unknown

511 (13.82)

346 (12.01)

23 (58.97)

128 (22.34)

14 (6.83)

Total cholesterol, mmol/L

4.25 (3.63, 4.95)

4.22 (3.63, 4.96)

4.28 (3.54, 4.95)

4.32 (3.68, 4.93)

4.18 (3.60, 4.90)

1.30^c

Triglyceride, mmol/L

1.24 (0.90, 1.84)

1.25 (0.89, 1.86)

1.03 (0.81, 1.71)

1.27 (0.92, 1.83)

1.12 (0.85, 1.54)

7.59^c

High-density lipoprotein cholesterol, mmol/L

1.14 (0.94, 1.35)

1.14 (0.92, 1.36)

1.17 ± 0.28

1.14 (0.97, 1.33)

1.11 (0.94, 1.36)

0.24^c

Low Density lipoprotein cholesterol, mmol/L

2.57 (2.10, 3.15)

2.51 (2.04, 3.14)

2.85 (2.42, 3.25)

2.70 (2.16, 3.20)

2.52 (2.09, 3.07)

16.16^c

Free Fatty Acids, mmol/L

0.36 (0.26, 0.60)

0.35 (0.26, 0.62)

0.36 (0.24, 0.62)

0.36 (0.26, 0.60)

0.35 (0.25, 0.54)

1.58^c

Apolipoprotein AI, g/L

1.28 (1.13, 1.49)

1.28 (1.12, 1.51)

1.22 ± 0.21

1.28 (1.13, 1.47)

1.36 (1.17, 1.50)

9.14^c

Apolipoprotein B, g/L

0.72 (0.61, 0.84)

0.73 (0.64, 0.82)

0.86 (0.69, 1.04)

0.72 (0.60, 0.88)

0.67 (0.51, 0.78)

19.60^c

Apolipoprotein A, mg/L

11.75 (4.77, 37.52)

10.15 (4.20, 28.45)

52.80 (35.60, 141.00)

14.00 (5.40, 47.70)

10.15 (4.38, 30.40)

41.40^c

Red blood cell, 10¹²/L

4.71 (4.37, 5.06)

4.68 (4.35, 5.03)

4.75 ± 0.57

4.75 (4.38, 5.09)

4.85 ± 0.60

10.25^c

Hemoglobin, g/L

141.00 (131.00, 154.00)

141.00 (130.00, 154.00)

142.59 ± 16.00

142.00 (132.00, 154.00)

146.20 ± 16.96

12.33^c

Hematocrit, %

42.00 (39.00, 46.00)

42.00 (39.00, 46.00)

0.43 (0.40, 0.49)

41.00 (6.17, 45.00)

44.00 (41.00, 47.00)

112.58^c

Mean corpuscular volume, fl

90.70 (87.80, 93.70)

90.70 (87.90, 93.70)

89.91 ± 4.63

90.60 (87.60, 93.90)

90.65 (87.70, 93.82)

1.59^c

Mean Corpuscular Hemoglobin, pg

30.30 (29.20, 31.50)

30.30 (29.10, 31.40)

30.16 ± 2.24

30.30 (29.20, 31.50)

30.55 (29.40, 31.80)

2.10^c

Mean corpuscular hemoglobin concentration, g/L

333.00 (328.00, 340.00)

333.00 (327.00, 339.00)

335.14 ± 12.15

334.00 (328.00, 340.00)

334.97 ± 9.47

7.94^c

Red Cell Distribution Width Coefficient of Variation, %

11.70 (11.20, 12.40)

11.70 (11.20, 12.20)

13.15 ± 0.82

12.00 (11.50, 12.80)

11.60 (11.10, 11.93)

107.03^c

Platelet, 10⁹/L

219.00 (181.00, 263.00)

218.00 (177.00, 262.00)

219.27 ± 47.67

219.00 (185.00, 267.00)

224.98 ± 64.67

1.32^c

Platelet distribution width, fl

17.00 (16.30, 17.60)

17.20 (16.60, 17.80)

12.80 ± 2.48

16.70 (12.80, 17.40)

17.15 (16.70, 17.60)

136.13^c

Mean platelet volume, fl

9.50 (8.40, 10.60)

9.40 (8.30, 10.50)

10.41 ± 1.28

9.70 (8.70, 10.80)

9.00 (8.07, 10.30)

31.87^c

Plateletcrit, %

0.20 (0.17, 0.24)

0.20 (0.17, 0.24)

0.23 ± 0.05

0.21 (0.18, 0.25)

0.20 (0.16, 0.23)

21.22^c

Red Cell Distribution Width - Standard Deviation, fl

42.60 (40.40, 45.10)

42.50 (40.30, 45.00)

43.52 ± 3.09

42.60 (40.25, 45.12)

41.50 ± 3.04

1.99^c

Platelet-larger cell ratio, %

27.75 (21.33, 33.18)

27.70 (20.90, 33.10)

29.69 ± 8.10

27.50 (21.45, 33.10)

24.77 ± 3.25

2.38^c

white blood cell, 10⁹/L

6.40 (5.30, 7.70)

6.30 (5.20, 7.60)

6.57 ± 1.81

6.50 (5.40, 7.96)

6.80 (5.70, 8.22)

18.03^c

Neutrophil percentage, %

65.15 ± 10.18

65.22 ± 10.02

61.18 ± 11.81

64.24 ± 10.52

68.02 ± 9.36

7.78 ^d

Lymphocyte percentage, %

25.80 (19.80, 32.15)

25.70 (19.90, 32.50)

28.74 ± 10.45

26.95 ± 9.42

23.80 ± 8.44

15.10^c

Monocytes percentage, %

6.80 (5.70, 8.00)

6.80 (5.70, 8.00)

7.26 ± 1.67

6.90 (5.80, 8.10)

6.90 (5.70, 7.93)

1.32^c

Eosinophil percentage, %

1.00 (0.55, 1.70)

1.00 (0.60, 1.60)

2.00 (0.70, 3.00)

1.00 (0.50, 1.90)

0.80 (0.40, 1.25)

20.72^c

Basophil percentage, %

0.20 (0.20, 0.30)

0.20 (0.10, 0.30)

0.50 (0.30, 0.70)

0.20 (0.20, 0.40)

0.20 (0.10, 0.20)

78.70^c

Absolute neutrophil count, 10⁹/L

4.10 (3.20, 5.30)

4.00 (3.19, 5.20)

4.05 ± 1.45

4.10 (3.17, 5.50)

4.50 (3.68, 5.80)

18.32^c

Absolute lymphocytes count, 10⁹/L

1.60 (1.22, 2.06)

1.60 (1.20, 2.00)

1.80 (1.30, 2.29)

1.70 (1.30, 2.17)

1.60 (1.20, 1.90)

19.05^c

Absolute monocyte count, 10⁹/l

0.40 (0.34, 0.52)

0.40 (0.30, 0.50)

0.48 ± 0.17

0.43 (0.38, 0.57)

0.50 (0.40, 0.60)

11.32^c

Absolute eosinophil count, 10⁹/L

0.10 (0.00, 0.10)

0.10 (0.00, 0.10)

0.10 (0.03, 0.19)

0.10 (0.00, 0.10)

0.10 (0.00, 0.10)

22.09^c

Absolute basophil count, 10⁹/L

0.00 (0.00, 0.00)

0.00 (0.00, 0.00)

0.03 (0.02, 0.05)

0.00 (0.00, 0.03)

0.00 (0.00, 0.00)

248.67^c

Antistreptolysin O, IU/ml

55.20 (32.60, 101.90)

56.10 (35.20, 98.88)

369.80(245.45, 494.15)

51.15 (29.98, 113.45)

51.00 (25.90, 110.70)

6.02^c

Rheumatoid factor, IU/ml

5.00 (3.00, 8.00)

5.00 (3.00, 8.00)

0.80(0.50, 1.10)

4.40 (2.80, 8.00)

4.00 (2.70, 7.00)

11.45^c

C-reactive protein, mg/L

1.60 (0.60, 3.50)

1.90 (0.88, 3.90)

2.15 (1.80, 4.67)

1.50 (0.52, 3.30)

1.30 (0.60, 2.80)

5.15^c

Serum amyloid A, mg/L

5.20 (3.10, 8.95)

6.10 (4.38, 12.63)

9.81 ± 11.57

4.90 (3.02, 9.25)

3.90 (2.95, 6.80)

8.89^c

Monocyte to high-density lipoprotein cholesterol ratio

0.40 (0.29, 0.54)

0.40 (0.29, 0.54)

0.49 ± 0.22

0.38 (0.28, 0.51)

0.43 (0.36, 0.59)

6.42^c

Monocyte-to-lymphocyte ratio

0.27 (0.21, 0.36)

0.27 (0.21, 0.36)

0.28 (0.21, 0.33)

0.26 (0.20, 0.34)

0.30 (0.23, 0.39)

11.23^c

Platelet-to-lymphocyte ratio

133.82 (101.57, 178.89)

135.62 (102.00, 183.12)

125.61 (95.44, 162.77)

129.22 (98.19, 166.92)

136.34 (107.06, 189.39)

9.54^c

Neutrophil-to-lymphocyte ratio

2.56 (1.81, 3.64)

2.56 (1.81, 3.62)

2.07 (1.60, 3.61)

2.46 (1.74, 3.44)

2.92 (2.07, 4.39)

18.11^c

Systemic immune-inflammation index

547.08 (369.26, 835.27)

548.84 (365.22, 814.27)

481.96 (343.45, 746.26)

529.71 (353.11, 810.14)

611.08 (434.84, 1003.79)

13.03^c

System inflammation response index

1.11 (0.73, 1.73)

1.10 (0.72, 1.69)

1.08 (0.74, 1.45)

1.07 (0.71, 1.74)

1.26 (0.89, 2.10)

16.30^c

Aggregate index of systemic inflammation

239.50 (150.18, 397.53)

234.65 (148.37, 386.26)

249.38 (162.33, 331.15)

233.39 (140.18, 399.84)

281.19 (184.49, 471.69)

12.55^c

Derived neutrophil to lymphocyte ratio

1.91 (1.41, 2.62)

1.90 (1.42, 2.62)

1.52 (1.26, 2.46)

1.88 (1.35, 2.47)

2.14 (1.61, 3.07)

19.50^c