Table 1 Demographic and clinical characteristics.

From: Association between metabolic syndrome, diabetes mellitus, inflammation and cognitive dysfunctions in schizophrenia: a cross-sectional analysis

 

SCZ (n = 103)

SCZ+MetS (n = 62)

SCZ + DM (n = 53)

Age (years)

43.3 ± 11.3

43.4 ± 11.5

44.0 ± 10.0

Sex (male/female)

69/34

41/21

37/16

Education (years)

11.7 ± 3.2

11.0 ± 2.8

12.2 ± 3.3

Illness duration (years)

14.8 ± 4.7

15.4 ± 5.2

16.1 ± 4.1

BMI

23.7 ± 3.2

33.8 ± 4.2a

34.5 ± 4.5a

Waist-to-hip ratio

0.7 ± 0.1

1.0 ± 0.07a

1.0 ± 0.08a

PANSS-P

21.5 ± 7.2

21.9 ± 9.0

22.1 ± 8.0

PANSS-N

24.3 ± 6.9

24.8 ± 8.7

25.7 ± 7.2

PANSS-G

49.5 ± 10.3

49.4 ± 11.3

50.5 ± 10.6

PSP

50.8 ± 8.6

53.2 ± 7.4

51.2 ± 8.9

Antipsychotic dose (CPZ-equivalent, mg/day)

409.7 ± 160.3

401.1 ± 159.3

443.9 ± 187.7

Antipsychotic type

olanzapine (n = 35)

risperidone/paliperidone (n = 39)

clozapine (n = 11)

aripiprazole (n = 9)

quetiapine (n = 8)

haloperidol (n = 1)

olanzapine (n = 20)

risperidone (n = 14)

quetiapine (n = 10)

aripiprazole (n = 11)

flupentixol (n = 5)

clozapine (n = 2)

olanzapine (n = 12)

risperidone/paliperidone (n = 23)

quetiapine (n = 10)

aripiprazole (n = 7)

zuclopenthixol (n = 1)

  1. Data are mean ( ± standard deviation) except sex and antipsychotic type.
  2. SCZ schizophrenia, MetS metabolic syndrome, DM diabetes mellitus, BMI body mass index, PANSS Positive and Negative Syndrome Scale, P positive symptoms, N negative symptoms, G general symptoms, PSP Personal and Social Performance scale, CPZ chlorpromazine.
  3. aSCZ < SCZ+MetS = SCZ + DM, p < 0.01, one-way ANOVA followed by Holm-corrected t-tests.