Table 2 Laboratory measures.

From: Association between metabolic syndrome, diabetes mellitus, inflammation and cognitive dysfunctions in schizophrenia: a cross-sectional analysis

 

SCZ (n = 103)

SCZ+MetS (n = 62)

SCZ + DM (n = 53)

Group comparisons

IL-6 (pg/mL)

8.3 ± 3.7

9.7 ± 4.5

13.8 ± 4.6

•SCZ < MetS, p = 0.03, d = 0.35

•SCZ < DM, p < 0.001, d = 1.4

•DM > MetS, p = 0.001, d = 0.9

CRP (mg/mL)

1.8 ± 1.0

1.8 ± 0.9

2.0 ± 1.2

•SCZ = MetS, p = 1, d = 0

•SCZ = DM, p = 0.3, d = 0.19

•DM = MetS, p = 0.3, d = 0.19

TG (mmol/L)

1.0 ± 0.4

2.1 ± 0.9

2.4 ± 1.0

•SCZ < MetS, p < 0.001, d = 1.7

•SCZ < DM, p < 0.001, d = 2.1

•DM = MetS, p = 0.1, d = 0.32

HDL (mmol/L)

1.8 ± 0.5

1.2 ± 0.4

1.2 ± 0.5

•SCZ > MetS, p < 0.001, d = 1.3

•SCZ > DM, p < 0.001, d = 1.2

•DM = MetS, p = 1, d = 0

LDL (mmol/L)

2.4 ± 0.7

2.8 ± 0.8

2.7 ± 0.8

•SCZ < MetS, p < 0.001, d = 0.54

•SCZ < DM, p = 0.02, d = 0.41

•DM = MetS, p = 0.5, d = 0.13

FBG (mmol/L)

4.0 ± 0.8

5.6 ± 1.2

7.6 ± 1.7

•SCZ < MetS, p < 0.001, d = 1.7

•SCZ < DM, p < 0.001, d = 3.0

•DM > MetS, p < 0.001, d = 1.4

HbA1c (%)

4.9 ±1.3

5.4 ± 1.5

7.1 ± 1.6

•SCZ < MetS, p = 0.03, d = 0.36

SCZ < DM, p < 0.001, d = 1.6

•DM > MetS, p < 0.001, d = 1.1

  1. Data are mean ( ± standard deviation) except sex and antipsychotic type.
  2. Group comparisons: one-way ANOVA followed by Holm-corrected t-tests, p<0.05; The “ < ” and “ > ” signs denote significant differences between the groups, whereas the “=” sign indicates no significant between-group difference.
  3. SCZ schizophrenia, MetS metabolic syndrome, DM diabetes mellitus, IL-6 interleukin 6, CRP C-reactive protein, TG triglyceride, HDL High Density Lipoprotein, LDL Low Density Lipoprotein, FBG fasting blood glucose, HbA1c Hemoglobin A1c.