Fig. 1: Associations between PRSSCZ and brain white matter IDPs.
A Brain white matter tracts whose microstructure metrics (FA, MD, MO, OD, ICVF, ISOVF, AD, and RD) demonstrate significant positive (warm color) or negative (cold color) correlations (P < 1.26 × 10−4) with PRSSCZ. B Bubble plot shows the associations between PRSSCZ and 384 brain white matter IDPs. A bubble represents an association between PRSSCZ and IDP. The x-axis shows 48 white matter tracts, while the y-axis shows eight metrics. The bubble size indicates the -log10(P) value and the bubble color indicates the T value of this association. ACR anterior corona radiata, AD axial diffusivity, ALIC anterior limb of internal capsule, BCC body of corpus callosum, CP cerebral peduncle, CST corticospinal tract, CgC cingulum cingulate gyrus, CgH cingulum hippocampus, EC external capsule, FA fractional anisotropy, FX fornix, FX/ST fornix cres and stria terminalis, GC genu of corpus callosum, IC inferior cerebellar peduncle, ICVF intracellular volume fraction, ISOVF isotropic volume fraction, L left, MCP middle cerebellar peduncle, MD mean diffusivity, ML medial lemniscus, MO mode of anisotropy, OD orientation dispersion, PCR posterior corona radiata, PCT pontine crossing tract, PLIC posterior limb of internal capsule, PTR posterior thalamic radiation, R right, RD radial diffusivity, RLIC retrolenticular part of internal capsule, SCC splenium of corpus callosum, SCP superior cerebellar peduncle, SCR superior corona radiata, SFO superior fronto-occipital fasciculus, SLF superior longitudinal fasciculus, SS sagittal stratum, TAP tapetum, UNC uncinate fasciculus.
