Fig. 3: Significant causal mediation effects. | Schizophrenia

Fig. 3: Significant causal mediation effects.

From: Polygenic risk for schizophrenia is associated with white matter microstructure, cognitive and mental health

Fig. 3: Significant causal mediation effects.

A The distribution of the 81 significant CMA results across the six behavioral phenotypes. B Total effects between PRSSCZ and behavioral phenotypes. C–H Top CMA results for associations between PRSSCZ and six behavioral phenotypes. ACME average causal mediation effects, ADE average direct effects, CP cerebral peduncle, FX/ST fornix cres and stria terminalis, L left, OD orientation dispersion, PRSSCZ polygenetic risk score for schizophrenia, PTR posterior thalamic radiation, R right, RD radial diffusivity.

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