Table 2 Mean N100 amplitude, T1w/T2w-ratio in AC1 and AC2 in SCZspect and HC.

From: Relationship between N100 amplitude and T1w/T2w-ratio in the auditory cortex in schizophrenia spectrum disorders

 

N100 amplitude (microvolts)

Mean (SE) [95% CI]

AC1 T1w/T2w-ratio

Mean (SE) [95% CI]

AC2 T1w/T2w-ratio

Mean (SE) [95% CI]

SCZspect [n = 33]

12.19 (1.29) [9.65–14.74]

0.89 (0.002) [0.88–0.89]

0.88 (0.002) [0.87–0.88]

HC [n = 144]

15.30 (0.61) [14.09–16.51]

0.89 (0.001) [0.89–0.89]

0.88 (0.001) [0.88–0.88]

SCZspect vs. HC

est = -3.11

est = -1.87e–04

est=7.20e–04

se=1.43

se=2.32e–03

se=2.34e–03

p = 0.03*

p = 0.94

p = 0.76

Cohen’s d = 0.42

Cohen’s d = 0.02

Cohen’s d = 0.06

Hedges´g = 0.42

Hedges´g = 0.02

Hedges´g = 0.06

  1. Table 2 shows mean N100 amplitude, T1w/T2w-ratio in AC1, primary auditory cortex and in AC2, secondary auditory cortex in SCZspect, schizophrenia spectrum disorder, and in HC, healthy controls. Estimated marginal means were calculated using analysis of covariance, where N100 amplitude, T1w/T2w-ratio in AC1 or T1w/T2w-ratio in AC2 were set as dependent variables with age, sex and diagnosis as independent variables. Estimated marginal means are provided with SE, standard error of the mean, and 95% CI, confidence interval. In addition, Table 2 shows differences in means between SCZspect and HC. Est, estimate; p, p-value; **, significant p-value (p < 0.017); *, nominally significant p-value that did not meet the adjusted threshold for statistical significance after Bonferroni correction. The bold values indicate significant or nominally significant p-values; N100 amplitude was nominally (p = 0.03) lower in SCZspect compared to HC. T1w/T2w-ratios in AC1/AC2 did not differ between SCZspect and HC.