Fig. 3: Group differences in functional connectivity networks (FCN) between SCZ and HC groups. | Schizophrenia

Fig. 3: Group differences in functional connectivity networks (FCN) between SCZ and HC groups.

From: Peripheral inflammation mediates cognitive deficits in drug-naive schizophrenia through hippocampal-thalamo-visual circuitry dysfunction

Fig. 3: Group differences in functional connectivity networks (FCN) between SCZ and HC groups.

A functional connectome circle showed significant group difference between SCZ and HC groups (FDR-corrected P-value < 0.05). The labels outside the circle stand for the 30 network-based cortical regions and 10 subcortical regions. Red curves indicate hyperconnectivity (SCZ > HC), with connection opacity scaled to t-statistic magnitude. B A 10 × 10 FC matrix visualizes dysregulated connections (cell opacity reflects t-statistics). C group comparisons of connectivity strength. SCZ schizophrenia, HC healthy controls. FC functional connectivity, FCN functional connectivity network. THA thalamus, AMYG amygdala, HIP hippocampus, DAN dorsal attention network, IPS intraparietal sulcus, SMN sensorimotor network. l left, r right.

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