Fig. 2: Post-treatment reduction in MSD at the whole-brain and network levels. | Schizophrenia

Fig. 2: Post-treatment reduction in MSD at the whole-brain and network levels.

From: Risperidone reduces individualized morphometric similarity deviation in schizophrenia and associates with cortical transcriptomic patterns

Fig. 2: Post-treatment reduction in MSD at the whole-brain and network levels.

A Group-averaged z-maps of MSD at baseline and after 12 weeks of treatment, along with the paired t-statistic map. Warm colors (red) in the first two maps indicate greater variability; cool colors (blue) indicate lower variability. In the t-map, red denotes increases and blue denotes decreases in MSD following treatment. B Boxplots showing group-level individual variability at the whole-brain and functional network levels. Orange and blue represent SZ0W and SZ12W, respectively. Asterisks denote statistically significant reductions after FDR correction (*pFDR < 0.05). Network labels: Vis, visual; SomMot, somatomotor; DorsAttn, dorsal attention; SalVentAttn, salience/ventral attention; Cont, control; SZ0W, schizophrenia at baseline; SZ12W, schizophrenia at 12 weeks post-treatment.

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