Fig. 7: Specific expression of the genes associated with changes of MSD. | Schizophrenia

Fig. 7: Specific expression of the genes associated with changes of MSD.

From: Risperidone reduces individualized morphometric similarity deviation in schizophrenia and associates with cortical transcriptomic patterns

Fig. 7

A The CSEA analysis revealed a significant association between the PLS1- genes and both oligodendrocyte and astrocytes. B Temporal specific expression analysis indicated that PLS1+ genes express post-late fetal stage, whereas PLS- genes express earlier. The color represents adjusted p values (BH-FDR). The sizes of the hexagons denote temporal specificity across different specificity index probability (pSI) statistic thresholds ranging from 0.05 to 1e-4. The outer hexagons correspond to the least specific test for a cell type (pSI threshold = 0.05), whereas the innermost hexagon reflects the most specific test for a cell type (pSI threshold = 1e-4). OPC, oligodendrocyte progenitor cells; Immu, immune cells; Pnoc + , prepronociceptin-expressing neurons; Ntsr + , corticothalamic neurons; Glt25d2, corticopontine neurons; Astro, Astrocytes; Cort + , corticosterone-expressing neurons; Myeli, myelinating oligodendrocytes; pSI, specificity index probability.

Back to article page