Fig. 5: The activity levels of MitoCom I–IV in the Nf-Con, Nf-apoE−/− and GSf-apoE−/− groups.

A The MitoCom I activity levels in the Nf-apoE−/− mice appeared to be lower than those in the NfCon group, and recovered in all GSf-apoE−/− mice. B Significantly reduced MitoCom II activity levels in the Nf-apoE−/− group compared to those in the Nf-Con group were recovered in all GSf-apoE−/− groups. C The reduced MitoCom III activity levels in the Nf-apoE−/− group compared to those in the Nf-Con group were recovered in all the GSf-apoE−/− groups. D MitoCom IV activity levels in the NfapoE−/− group were similar to those in the Nf-Con group. All GSf-apoE−/− groups showed significantly higher MitoCom IV activity levels than the Nf-Con group. E Significantly lower ATP levels in the NfapoE−/− group compared to those in the Nf-Con group were recovered or higher in all GSf-apoE−/−groups.