Fig. 2: Heart histopathological features observed in control, hypercholesterolemic, and treated rats are depicted in (A–J). | npj Science of Food

Fig. 2: Heart histopathological features observed in control, hypercholesterolemic, and treated rats are depicted in (A–J).

From: Investigating the anti-hypolipidemic effects of croissants enriched with fruit byproducts in a rat model

Fig. 2

A Control rats exhibited normal cardiac muscle fiber and vascular tissue histology. B, C Rats on a hypercholesterolemic diet showed fatty changes in cardiomyocytes, inflammatory cell infiltration (IF), and changes in the tunica intima of some cardiac blood vessels. D In hypercholesterolemic rats treated with 40% croissants, heart tissue analysis indicated moderate cardiomyocyte fat globules. In hypercholesterolemic rats treated with 10% E or 15% F OP, some cardiomyocytes showed hyaline degeneration and vacuolation. G Rats fed a hypercholesterolemic diet with 10% WR, displayed vacuolation in a limited number of myocardial bundles. H Rats fed with 15% WR presented apparently normal histological sections in most areas of the heart muscle. I Vacuolated cardiomyocytes were observed in the heart sections of hypercholesterolemic rats that consumed 10% MP. J Heart tissues of rats fed 15% MP showed infiltration of a small number of leukocytes, NCM, FG, and IF (scale bar 20 µm).

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