Fig. 5: Identification of umami peptides from fish sauce and interactions with T1R1/T1R3.

A The MW distribution of the detected peptides with a score above 40. B Amino acid composition of the detected peptides with a score above 40. C Virtual screening results based on toxicity, MW, allergenicity, water solubility, stability, and bitterness of peptides. D The stereo diagram of AEREIVRDIKEK into the T1R1/T1R3 active-site cavity. E The 3D binding mode of AEREIVRDIKEK to T1R1/T1R3. F The 2D molecular docking of the binding of AEREIVRDIKEK to T1R1/T1R3. G The stereo diagram of NWDDMEK into the T1R1/T1R3 active-site cavity. H The 3D binding mode of NWDDMEK to T1R1/T1R3. I The 2D molecular docking of the binding of NWDDMEK to T1R1/T1R3.