Fig. 3: Number of statistically significant differentially abundant proteins and enriched Kegg pathways.

A Volcano plot showing 2039 proteins when a comparison was made between non-induced and induced preadipocytes, out of which 459 proteins had statistically significant q-value of less than 0.05. The non-significant proteins (q-value < 0.05) are shown in black; the significant proteins (q-value > 0.05) with a fold change greater than 1 are represented in dark blue, while those with a fold change less than 1 are shown in light blue. B The bar graph shows enriched KEGG pathway results generated through the WebGestalt database with p-values lower than 0.05 indicated through an asterisk (*). The significant pathways are further listed with the specific genes that were associated. (NOTCH1 notch receptor 1, NUMBL NUMB like endocytic adaptor protein, APOB apolipoprotein B, APOC3 apolipoprotein C3, CYP27A1 cytochrome P450 family 27 subfamily A member 1, SCD stearoyl-CoA desaturase). (Fig. 3B created using GraphPad Prism).