Table 2 Primary and secondary outcomes in the intention to treat seta

From: Effects of Lactiplantibacillus plantarum on moderate dyslipidemia before medication involving gut microbiota and host genetics

Outcome

Group

Pb

LP group

PLA group

Group

Time

Group × Time

LDL-C, mmol/L

  

0.947

< 0.001

0.078

Week 0

3.951 (0.544)

3.884 (0.635)

   

Week 6

4.099 (0.585)

4.010 (0.632)

   

Week 12

3.868 (0.610)

3.943 (0.616)

   

ΔWeek 6

0.159 (0.559)

0.086 (0.403)

   

ΔWeek 12

−0.065 (0.597)

0.011 (0.413)

   

TC, mmol/L

  

0.845

< 0.001

0.055

Week 0

5.793 (0.722)

5.759 (0.746)

   

Week 6

5.996 (0.740)

5.914 (0.766)

   

Week 12

5.710 (0.767)

5.840 (0.744)

   

ΔWeek 6

0.204 (0.642)

0.124 (0.479)

   

ΔWeek 12

−0.075 (0.686)

0.042 (0.499)

   

TG, mmol/L

  

0.454

< 0.001

0.640

Week 0

2.387 (0.752)

2.540 (1.502)

   

Week 6

2.675 (1.137)

2.762 (1.420)

   

Week 12

2.317 (0.833)

2.487 (0.910)

   

ΔWeek 6

0.290 (0.898)

0.227 (1.494)

   

ΔWeek 12

−0.100 (0.864)

−0.074 (1.292)

   

HDL-C, mmol/L

  

0.930

0.180

0.834

Week 0

1.075 (0.208)

1.097 (0.228)

   

Week 6

1.091 (0.210)

1.089 (0.202)

   

Week 12

1.108 (0.208)

1.104 (0.221)

   

ΔWeek 6

0.010 (0.121)

0.006 (0.124)

   

ΔWeek 12

0.029 (0.128)

0.025 (0.124)

   

INS, μU/mL

  

0.930

0.099

0.415

Week 0

12.425 (11.369)

10.728 (4.809)

   

Week 6

10.741 (6.897)

11.131 (5.259)

   

Week 12

11.771 (9.179)

11.512 (5.385)

   

ΔWeek 6

−1.831 (6.329)

0.109 (4.057)

   

ΔWeek 12

−0.897 (5.559)

0.390 (4.226)

   

GLU, mmol/L

  

0.468

0.418

0.258

Week 0

5.061 (0.340)

5.158 (0.559)

   

Week 6

5.113 (0.519)

5.137 (0.516)

   

Week 12

5.042 (0.450)

5.149 (0.624)

   

ΔWeek 6

0.049 (0.407)

−0.004 (0.425)

   

ΔWeek 12

−0.024 (0.379)

0.014 (0.415)

   

BMI, kg/m2

  

0.176

0.532

0.756

Week 0

26.162 (4.631)

24.419 (4.142)

   

Week 6

26.074 (6.148)

25.090 (5.087)

   

Week 12

26.501 (5.629)

25.139 (3.916)

   

ΔWeek 6

0.060 (4.215)

0.285 (3.832)

   

ΔWeek 12

0.236 (4.117)

0.269 (3.878)

   
  1. Data are mean (SD).
  2. aWeek 0 (group 1: n = 67, group 2: n = 68), week 6 (group 1: n = 61, group 2: n = 60), week 12 (group 1: n = 61, group 2: n = 59).
  3. bP values were determined by generalized estimating equation (GEE) adjusted for age, sex, baseline BMI, and corresponding baseline outcome measurement.
  4. BMI body mass index, GLU glucose, HDL-C high-density lipoprotein, INS insulin, LDL-C low-density lipoprotein cholesterol, LP Lactiplantibacillus plantarum, PLA placebo, TC total cholesterol, TG triglyceride.
Back to article page