Table 1 Baseline characteristics of infants with bronchiolitis

From: Integrated-omics analysis with explainable deep networks on pathobiology of infant bronchiolitis

 

Overall

Characteristics

(n = 397)

Demographics

 Age (month), median (IQR)

3 (2–7)

 Female sex

165 (42)

Race/ethnicity

 Non-Hispanic white

160 (40)

 Non-Hispanic black

91 (23)

 Hispanic

129 (33)

 Other or unknown

17 (4)

Prematurity (32.0–36.9 weeks)

72 (18)

C-section delivery

138 (35)

Previous breathing problems (count)

 0

313 (79)

 1

62 (16)

 2

22 (6)

Previous ICU admission

6 (2)

History of eczema

61 (15)

Ever attended daycare

94 (24)

Cigarette smoke exposure at home

60 (15)

Parental history of eczema

79 (20)

Parental history of asthma

138 (35)

Clinical presentation at index hospitalization

 Weight at presentation (kg), median (IQR)

6 (5–8)

 Respiratory rate (per minute), median (IQR)

50 (40–60)

 Oxygen saturation

  <90%

37 (10)

  90-93%

56 (15)

  ≥94%

293 (76)

 Blood eosinophilia ( ≥ 4%)

34 (9)

 IgE sensitization

81 (20)

Respiratory virus

 RSV infection

316 (80)

 RV infection

86 (22)

 RSV/RV coinfection

47 (12)

 Other pathogena only

32 (8)

Clinical outcomes

 Respiratory supportb

79 (20)

 Positive pressure ventilation usec

25 (6)

  1. Note: Data are no. (%) of infants unless otherwise indicated. Percentages may not equal 100, because of rounding and missingness.
  2. ICU intensive care unit, IgE immunoglobulin E, IQR interquartile range, RSV respiratory syncytial virus, RV rhinovirus.
  3. aAdenovirus, bocavirus, Bordetella pertussis, enterovirus, human coronavirus NL63, OC43, 229E, or HKU1, human metapneumovirus, influenza A or B virus, Mycoplasma pneumoniae, and parainfluenza virus 1–3.
  4. bInfants with bronchiolitis who underwent continuous positive airway ventilation and/or mechanical ventilation and/or high-flow oxygen.
  5. cInfants with bronchiolitis who underwent continuous positive airway ventilation and/or mechanical ventilation.