Fig. 3: Resonance of abolished bioluminescence rhythm by periodic temperature pulses. | npj Systems Biology and Applications

Fig. 3: Resonance of abolished bioluminescence rhythm by periodic temperature pulses.

From: Low temperature abolishes human cellular circadian rhythm through Hopf bifurcation

Fig. 3

A Bioluminescence rhythms of cultured U2OS BMAL1-dLuc reporter cells were subjected by periodic 1-h 37 °C pulses, administered at intervals of T = 18, 24, or 30 hours against a constant 30 °C (H: 37 °C; L: 30 °C). B The amplitude of forced bioluminescence oscillations under periodic temperature pulses. Amplitude was quantified using the SD on time-course data after 2T under 30 °C. The blue baseline indicates the amplitude at constant 30 °C conditions.

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