Fig. 3: Association of the primary immunogenicity marker levels at M21 and hazard of malaria during the following 11 months in the R3R (RTS,S-boosted) and R3C (RTS,S-unboosted) vaccine groups. | npj Vaccines

Fig. 3: Association of the primary immunogenicity marker levels at M21 and hazard of malaria during the following 11 months in the R3R (RTS,S-boosted) and R3C (RTS,S-unboosted) vaccine groups.

From: Effect of RTS,S/AS01E vaccine booster dose on cellular immune responses in African infants and children

Fig. 3

Hazard ratios indicate the factor by which the hazard is estimated to increase or decrease for one standard deviation change in the cytokine relative concentrations (ratio). Association of the primary immunogenicity markers with hazard of malaria in (a) children and infants together; (b) children only; and (c) infants only. Significance was tested with a Wald test on the corresponding Cox regression coefficient used to obtain hazard ratios. No significant differences were found following Benjamini-Hochberg adjustment.

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